SCHEMBL6510175

SCHEMBL6510175

COc1ccccc1-c1nc2ccccc2n1C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.62
LMNA P02545 3/20 0.62
HTT P42858 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
PDE10A Q9Y233 2/20 0.58
PDE2A O00408 1/20 0.58
RAB9A P51151 8/20 0.56
NPC1 O15118 6/20 0.56
SMN1; SMN2 Q16637 5/20 0.56
TP53 P04637 3/20 0.56
ALDH1A1 P00352 6/20 0.53
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
GAA P10253 3/20 0.50
MAPT P10636 2/20 0.50
HPGD P15428 2/20 0.50
PKM P14618 2/20 0.50
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50
METAP2 P50579 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29545613 0.84 RAB9A (0.62) KDM4ELMNAHTTNPSR1PDE10A
SCHEMBL3195186 0.83 ALDH1A1 (0.47) KDM4ELMNAHTTNPSR1PDE10A
SCHEMBL3184560 0.83 KDM4E (0.48) KDM4ELMNAHTTNPSR1PDE10A
SCHEMBL15228166 0.82 HSD11B1 (0.56) KDM4ELMNAHTTNPSR1PDE10A
SCHEMBL15228172 0.81 RAB9A (0.49) KDM4ELMNAHTTNPSR1RAB9A
SCHEMBL8023830 0.80 RECQL (0.58) KDM4ELMNAHTTNPSR1PDE10A
SCHEMBL24497555 0.80 MEN1 (0.48) KDM4ELMNAHTTRAB9ANPC1
SCHEMBL24462384 0.80 NPC1 (0.47) KDM4ELMNAHTTNPSR1RAB9A
SCHEMBL16692197 0.80 MEN1 (0.57) KDM4ELMNAHTTRAB9ANPC1
SCHEMBL12648806 0.80 MEN1 (0.57) KDM4ELMNAHTTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337519-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230292600-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2023-09-14 US disclosed
US-20230125206-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-20050239767-A1 Intermolecular SNAr of the heterocycle-activated nitro and fluoro groups-application in the synthesis of polyazamacrocyclic ligands NATIONAL SCIENCE FOUNDATION 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230125206-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, ODC1, OCIAD2 KDM4E 1449/4885LMNA 405/4885HTT 3500/4885
US-20050239767-A1 Intermolecular SNAr of the heterocycle-activated nitro and fluoro groups-application in the synthesis of polyazamacrocyclic ligands TECR, PAICS, DCXR KDM4E 1602/4885LMNA 1745/4885HTT 3764/4885
US-20230337519-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, YBX3, LBR KDM4E 2057/4885LMNA 132/4885HTT 3628/4885
US-20230292600-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OCIAD1, OCIAD2, OXER1 KDM4E 4308/4885LMNA 4764/4885HTT 4540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.