Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4000892 | 0.84 | CA12 (0.38) | CA1CA2CA9L3MBTL1CA12 | |
| SCHEMBL390917 | 0.74 | ALDH1A1 (0.48) | CA1CA2CA9L3MBTL1CA12 | |
| SCHEMBL393315 | 0.72 | CA2 (0.54) | CA1CA2CA9L3MBTL1CA12 | |
| SCHEMBL31095544 | 0.72 | CA2 (0.54) | CA1CA2CA9L3MBTL1CA12 | |
| SCHEMBL392853 | 0.69 | CA12 (0.55) | CA1CA2CA9CA12CYP2C9 | |
| SCHEMBL19099945 | 0.66 | GAA (0.41) | L3MBTL1PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL3244812 | 0.65 | L3MBTL1 (0.42) | CA1CA2CA9L3MBTL1CA12 | |
| SCHEMBL9175606 | 0.64 | L3MBTL1 (0.61) | CA1CA2CA9L3MBTL1CA12 | |
| SCHEMBL23226730 | 0.64 | ADRB3 (0.56) | — | |
| SCHEMBL6573116 | 0.64 | EP300 (0.50) | L3MBTL1POLBMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019191-A2 | 1, 1-DIOXIDO-4H-1,2,4-BENZOTHIADIAZINE DERIVATE UND VERWANDTE VERBINDUNGEN ALS INHIBITOREN DER HCV POLYMERASE ZUR BEHANDLUNG VON HEPATITIS C | ABBOTT LABORATORIES (US) | 2005-03-03 | — | — | WO | disclosed |