Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cyclopentanamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexylamine SCHEMBL7322768 | 0.97 | ALDH1A1 (0.41) | — | |
| Cycloheptanamine SCHEMBL11457856 | 0.97 | ALDH1A1 (0.41) | — | |
| Cyclooctanamine SCHEMBL11463223 | 0.97 | ALDH1A1 (0.41) | — | |
| Alcohol SCHEMBL11461188 | 0.97 | ALDH1A1 (0.41) | — | |
| Alcohol SCHEMBL28440813 | 0.87 | ALDH1A1 (0.43) | — | |
| Cyclohexylamine SCHEMBL4447887 | 0.84 | SHBG (0.39) | — | |
| Cyclopentanamine SCHEMBL3384335 | 0.83 | — | — | |
| Cyclohexylamine SCHEMBL20703173 | 0.81 | EPHX1 (0.38) | — | |
| Cyclohexylamine SCHEMBL2067439 | 0.81 | CYP1A2 (0.42) | — | |
| Cyclohexylamine SCHEMBL23319729 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037828-A1 | NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD. (KR) | 2005-04-28 | — | — | WO | disclosed |
| US-4223138-A | VAPORIZATION, CONDENSATION, RETARDING FLOW TO REACTION ZONE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-16 | — | — | US | disclosed |