Cyclohexylamine

Cyclohexylamine

SCHEMBL7322768

CCO.NC1CCCCC1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Cyclohexylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MMP8 known ✓ P22894 2/20 0.40
MMP1 known ✓ P03956 1/20 0.40
ALDH1A1 P00352 2/20 0.41
MMP2 P08253 1/20 0.38
NAAA Q02083 1/20 0.36
SHBG P04278 1/20 0.36
EPHX1 P07099 1/20 0.35
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL11461188 1.00 ALDH1A1 (0.41) ALDH1A1MMP8MMP1MMP2NAAA
Cyclooctanamine SCHEMBL11463223 1.00 ALDH1A1 (0.41) ALDH1A1MMP8MMP1MMP2NAAA
Cycloheptanamine SCHEMBL11457856 1.00 ALDH1A1 (0.41) ALDH1A1MMP8MMP1MMP2NAAA
Cyclopentanamine SCHEMBL6510288 0.97
Cyclohexylamine SCHEMBL4447887 0.88 SHBG (0.39) ALDH1A1MMP8MMP1MMP2SHBG
Alcohol SCHEMBL27543257 0.87
Cyclohexylamine SCHEMBL2067439 0.85 CYP1A2 (0.42) ALDH1A1MMP8MMP1MMP2SHBG
Cyclohexylamine SCHEMBL20703173 0.85 EPHX1 (0.38) ALDH1A1MMP8MMP1MMP2SHBG
Cyclohexylamine SCHEMBL23319729 0.84
Cycloheptanamine SCHEMBL2204676 0.84 THRB (0.41) ALDH1A1MMP8MMP1MMP2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-213131969-U Rotary evaporator for producing trans-4-aminocyclohexane ethanol 泰州精英化成医药科技有限公司 2021-05-07 CN claimed
CN-105247021-B Additive composition and industrial process fluid 福斯油品欧洲股份公司 2018-02-09 CN claimed
CN-105247021-A Additive composition and industrial process fluid FUCHS PETROLUB SE 2016-01-13 CN claimed
CN-120077104-A Resin composition, cured product, laminate, method for producing cured product, method for producing laminate, method for producing semiconductor device, and semiconductor device 富士胶片株式会社 2025-05-30 CN disclosed
CN-119968421-A Resin composition, cured product, laminate, method for producing cured product, method for producing laminate, method for producing semiconductor device, and semiconductor device 富士胶片株式会社 2025-05-09 CN disclosed
CN-119731595-A Resin composition, cured product, laminate, method for producing cured product, method for producing laminate, method for producing semiconductor device, and semiconductor device 富士胶片株式会社 2025-03-28 CN disclosed
CN-118244583-A Negative photosensitive polyimide precursor resin composition 深圳先进电子材料国际创新研究院 2024-06-25 CN disclosed
CN-116909100-B Photosensitive polyimide precursor composition 深圳先进电子材料国际创新研究院 2024-03-19 CN disclosed
CN-116909100-A Photosensitive polyimide precursor composition 深圳先进电子材料国际创新研究院 2023-10-20 CN disclosed
CN-116710498-A Polyimide precursor resin composition and method for producing same 旭化成株式会社 2023-09-05 CN disclosed
CN-116609998-A Polyimide precursor, negative photosensitive resin composition, and method for producing cured relief pattern using same 旭化成株式会社 2023-08-18 CN disclosed
CN-213131969-U Rotary evaporator for producing trans-4-aminocyclohexane ethanol 泰州精英化成医药科技有限公司 2021-05-07 CN disclosed
CN-111375447-A Modified cation exchange resin and preparation method and application thereof 中国石油化工股份有限公司 2020-07-07 CN disclosed
CN-109718754-A A kind of vanadium silver nickel metal oxide catalyst, preparation method and applications 中国石油化工股份有限公司 2019-05-07 CN disclosed
CN-105247021-B Additive composition and industrial process fluid 福斯油品欧洲股份公司 2018-02-09 CN disclosed
CN-104437622-B allyl acetate catalyst and preparation method thereof 中国石油化工股份有限公司 2016-08-10 CN disclosed
CN-105247021-A Additive composition and industrial process fluid FUCHS PETROLUB SE 2016-01-13 CN disclosed
US-5710321-A Process for preparing the cyclohexylamine salt of (+) - threo-2-hydroxy-3-(2'-aminophenylthio) -3-(4\"-methoxyphenyl) -propionic acid and of its (-) -antipode\ F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) 1998-01-20 US disclosed
EP-0311378-B1 6-Substituted alkoxy-2-oxo-1, 2-dihydroquinoxaline derivatives ASAHI CHEMICAL IND (JP) 1994-04-27 EP disclosed
US-4223138-A VAPORIZATION, CONDENSATION, RETARDING FLOW TO REACTION ZONE BAYER AKTIENGESELLSCHAFT (DE) 1980-09-16 US disclosed