Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654494 | 0.84 | KMT2A (0.45) | L3MBTL1KMT2AMEN1ESR1ESR2 | |
| SCHEMBL8756138 | 0.83 | L3MBTL1 (0.49) | CA2CA9L3MBTL1KMT2AMEN1 | |
| SCHEMBL7619544 | 0.81 | KMT2A (0.43) | L3MBTL1KMT2AMEN1ESR1ESR2 | |
| SCHEMBL19280308 | 0.81 | CA2 (0.42) | CA2CA9KMT2AMEN1NFE2L2 | |
| SCHEMBL6411427 | 0.80 | KMT2A (0.42) | CA2L3MBTL1KMT2AMEN1ESR1 | |
| SCHEMBL3620171 | 0.78 | KMT2A (0.41) | CA2L3MBTL1KMT2AMEN1ESR1 | |
| SCHEMBL71839 | 0.78 | KMT2A (0.41) | L3MBTL1KMT2AMEN1ESR1ESR2 | |
| SCHEMBL8746193 | 0.78 | GAA (0.48) | L3MBTL1KMT2AMEN1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL27691765 | 0.78 | KMT2A (0.41) | CA2L3MBTL1KMT2AMEN1ESR1 | |
| SCHEMBL2762565 | 0.78 | KMT2A (0.41) | L3MBTL1KMT2AMEN1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240252657-A1 | HEMTAC SMALL-MOLECULE DEGRADATION AGENT AND APPLICATION THEREOF | SHANDONG UNIVERSITY (CN) | 2024-08-01 | — | — | US | disclosed |
| EP-4306528-A1 | HEMTAC SMALL MOLECULE DEGRADATION AGENT AND USE THEREOF | Shandong University (CN) | 2024-01-17 | — | — | EP | disclosed |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | ELI LILLY AND COMPANY | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240252657-A1 | HEMTAC SMALL-MOLECULE DEGRADATION AGENT AND APPLICATION THEREOF | HSP90AB1, HSP90AA1, HSP90AB2P | CA2 3554/4885CA9 4071/4885L3MBTL1 1612/4885 |
| US-20050020684-A1 | Modulators of peroxisome proliferator activated receptors | NCOA4, PPARG, PPARA | CA2 2411/4885CA9 2750/4885L3MBTL1 3898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.