Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906715 | 0.77 | POLB (0.55) | POLBSMN1; SMN2PTPN1ALDH1A1KDM4E | |
| SCHEMBL3373253 | 0.76 | P2RX4 (0.47) | POLBSMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL27620887 | 0.73 | EGFR (0.45) | POLBL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL8431590 | 0.70 | PARP1 (0.44) | MAT2APOLBRAB9AALDH1A1KDM4E | |
| SCHEMBL9147581 | 0.68 | KDM4E (0.43) | POLBSMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5201509 | 0.67 | TP53 (0.47) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL9496147 | 0.67 | CA12 (0.50) | POLBSMN1; SMN2RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL6142952 | 0.67 | HPGD (0.57) | POLBSMN1; SMN2RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL30254498 | 0.66 | DDB1 (0.41) | POLBPTPN1NPC1RAB9AL3MBTL1 | |
| SCHEMBL27996393 | 0.66 | POLB (0.42) | POLBSMN1; SMN2PTPN1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005035526-A1 | BICYCLIC COMPOUNDS AND THEIR THERAPEUTIC USE | ARGENTA DISCOVERY LTD. (GB) | 2005-04-21 | — | — | WO | disclosed |