Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28853394 | 0.83 | DAO (0.41) | TP53KDM4ETSHRMCL1MEN1 | |
| SCHEMBL6471856 | 0.80 | MCL1 (0.39) | TP53KDM4ETSHRMCL1MAPT | |
| SCHEMBL28907783 | 0.79 | HDAC10 (0.43) | TP53KDM4ETSHRMCL1ALDH1A1 | |
| SCHEMBL5227447 | 0.79 | ALDH1A1 (0.56) | KDM4EMCL1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL17594938 | 0.79 | ALDH1A1 (0.45) | KDM4ETSHRMEN1KMT2AMAPT | |
| SCHEMBL28790758 | 0.79 | ACLY (0.43) | NPC1RAB9AHPGDLMNA | |
| SCHEMBL28548039 | 0.77 | POLB (0.52) | TP53KDM4ETSHRMCL1MEN1 | |
| SCHEMBL9496147 | 0.76 | CA12 (0.50) | KDM4ETSHRMCL1KMT2AMAPT | |
| SCHEMBL670199 | 0.76 | SMN1; SMN2 (0.47) | TP53KDM4ETSHRMCL1MEN1 | |
| SCHEMBL9849390 | 0.75 | IRAK4 (0.44) | KDM4EMCL1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1829872-B1 | PROCESSES FOR PRODUCTION OF INDOLE COMPOUNDS | NISSAN CHEMICAL IND LTD (JP) | 2015-07-29 | — | — | EP | disclosed |
| EP-1829872-A1 | PROCESSES FOR PRODUCTION OF INDOLE COMPOUNDS | Nissan Chemical Industries, Ltd. (JP) | 2007-09-05 | — | — | EP | disclosed |