Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785620 | 0.77 | CYP3A4 (0.43) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL6513026 | 0.76 | MEN1 (0.50) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL3789429 | 0.76 | CYP3A4 (0.48) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL7453199 | 0.71 | CYP3A4 (0.56) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL19631183 | 0.71 | CYP3A4 (0.46) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL6514605 | 0.71 | MEN1 (0.48) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL18129367 | 0.71 | CYP1A2 (0.49) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL5974847 | 0.70 | KDM4E (0.49) | TSHRALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL11298759 | 0.68 | CYP3A4 (0.48) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL10904140 | 0.68 | DHFR (0.43) | CYP3A4ALDH1A1TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050050594-A1 | Tryptophan synthase as a site of herbicide action | RODAWAY SHIRLEY (US) | 2005-03-03 | — | — | US | claimed |
| EP-1144672-A3 | TRYPTOPHAN SYNTHASE AS A SITE OF HERBICIDE ACTION | AMERICAN CYANAMID COMPANY (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000046394-A9 | TRYPTOPHAN SYNTHASE AS A SITE OF HERBICIDE ACTION | AMERICAN CYANAMID CO (US) | 2001-10-18 | — | — | WO | disclosed |
| EP-1144672-A2 | TRYPTOPHAN SYNTHASE AS A SITE OF HERBICIDE ACTION | AMERICAN CYANAMID COMPANY (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000046394-A2 | TRYPTOPHAN SYNTHASE AS A SITE OF HERBICIDE ACTION | AMERICAN CYANMID COMPANY (US) | 2000-08-10 | — | — | WO | disclosed |