Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1436075 | 0.82 | CYP2D6 (0.50) | CYP1A2CYP2D6TDP1TP53NR2F2 | |
| SCHEMBL5185226 | 0.80 | CYP1A2 (0.49) | CYP1A2CYP2D6TDP1TP53NR2F2 | |
| SCHEMBL5853005 | 0.78 | HPGD (0.47) | CYP1A2CYP2D6TDP1TP53NR2F2 | |
| SCHEMBL13321630 | 0.73 | CYP1A2 (0.43) | CYP1A2CYP2D6TDP1NR2F2ALDH1A1 | |
| SCHEMBL4265450 | 0.72 | TDP1 (0.49) | CYP1A2CYP2D6TDP1TP53ALDH1A1 | |
| SCHEMBL1145555 | 0.72 | TP53 (0.48) | CYP1A2CYP2D6TDP1TP53ALDH1A1 | |
| SCHEMBL7268486 | 0.71 | HPGD (0.58) | CYP2D6TDP1TP53ALDH1A1CYP3A4 | |
| SCHEMBL224923 | 0.71 | TP53 (0.52) | CYP1A2CYP2D6TDP1TP53ALDH1A1 | |
| SCHEMBL21102148 | 0.71 | CYP1A2 (0.48) | CYP1A2CYP2D6TDP1NR2F2ALDH1A1 | |
| SCHEMBL6541714 | 0.71 | TDP1 (0.44) | CYP1A2CYP2D6TDP1TP53NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071560-B1 | N-ACYLIMINO HETEROCYCLIC COMPOUNDS | BASF SE (DE) | 2018-01-10 | — | — | EP | disclosed |
| US-9783523-B2 | N-acylimino heterocyclic compounds | BASF SE (DE) | 2017-10-10 | — | — | US | disclosed |
| US-20160297793-A1 | N-ACYLIMINO HETEROCYCLIC COMPOUNDS | BASF SE (DE) | 2016-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297793-A1 | N-ACYLIMINO HETEROCYCLIC COMPOUNDS | CBR3, C5, ALOX5 | CYP1A2 555/4885CYP2D6 1033/4885TDP1 4628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.