Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781267 | 0.83 | SLC6A2 (0.51) | CYP3A4ALDH1A1ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL5166565 | 0.81 | MAPT (0.40) | CYP3A4ALDH1A1ALOX15TSHRTDP1 | |
| SCHEMBL3795007 | 0.80 | HPGD (0.41) | CYP3A4ALDH1A1ALOX15SMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL8948328 | 0.79 | GAA (0.43) | CYP3A4ALDH1A1ALOX15TDP1HSD17B10 | |
| SCHEMBL14219137 | 0.79 | NPC1 (0.55) | CYP3A4ALDH1A1ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL30422063 | 0.78 | CYP3A4 (0.52) | CYP3A4ALDH1A1ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL3783594 | 0.78 | CYP3A4 (0.52) | CYP3A4ALDH1A1ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL11101935 | 0.78 | ALDH1A1 (0.40) | CYP3A4ALDH1A1ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL7453199 | 0.78 | CYP3A4 (0.56) | CYP3A4ALDH1A1ALOX15TSHRSMN1; SMN2 | |
| SCHEMBL23302326 | 0.78 | SLC6A4 (0.41) | HSD17B10KMT2AMEN1NPC1APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2668186-B1 | PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES | SK BIOPHARMACEUTICALS CO LTD (KR) | 2017-05-03 | — | — | EP | disclosed |
| CN-104379568-A | Quinazolinedione derivative | CHUGAI PHARMACEUTICAL CO LTD | 2015-02-25 | — | — | CN | disclosed |
| US-8716309-B2 | Pharmaceutical composition comprising pyridone derivatives | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2014-05-06 | — | — | US | disclosed |
| EP-2668186-A1 | PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES | SK Biopharmaceuticals Co., Ltd. (KR) | 2013-12-04 | — | — | EP | disclosed |
| US-20130317059-A1 | PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2013-11-28 | — | — | US | disclosed |
| WO-2012102580-A1 | PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2012-08-02 | — | — | WO | disclosed |
| EP-1473332-B1 | INK COMPOSITION AND METHOD OF INK-JET RECORDING | FUJIFILM CORP (JP) | 2011-05-25 | — | — | EP | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| EP-0212301-B1 | PROCESS FOR THE PREPARATION OF 2-AMINOPHENYL THIOETHERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-24 | — | — | EP | disclosed |
| US-4808752-A | REACTING 2-AMINOBENZOTHIAZOLES WITH ALKALI HYDROXIDES; ALKYLATING AND HYDROLYZING THE RESULTING MERCAPTOPHENYLUREA SALT | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-02-28 | — | — | US | disclosed |
| EP-0212301-A2 | Process for the preparation of 2-aminophenyl thioethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | CYP3A4 177/4885ALDH1A1 4339/4885ALOX15 1941/4885 |
| US-20130317059-A1 | PHARMACEUTICAL COMPOSITION COMPRISING PYRIDONE DERIVATIVES | PLPBP, PDXK, PIR | CYP3A4 22/4885ALDH1A1 2259/4885ALOX15 1714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.