SCHEMBL6510644

SCHEMBL6510644

Cc1nc(C)nc(-c2cc(C(C)(C)C)ccc2O)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
HSD17B10 Q99714 2/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MAPT P10636 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
GAA P10253 1/20 0.46
PKM P14618 1/20 0.46
RECQL P46063 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.42
CYP2D6 P10635 2/20 0.40
SIRT1 Q96EB6 1/20 0.40
ESR1 P03372 1/20 0.40
HSP90AA1 P07900 2/20 0.40
NPC1 O15118 5/20 0.39
HSP90AB1 P08238 1/20 0.36
LMNA P02545 1/20 0.36
TYR P14679 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29785519 0.79 ALDH1A1 (0.70) ALDH1A1HSD17B10HPGDALOX15TDP1
SCHEMBL6240718 0.79 ALDH1A1 (0.70) ALDH1A1HSD17B10HPGDALOX15TDP1
SCHEMBL6511484 0.78 ALDH1A1 (0.47) ALDH1A1HSD17B10HPGDALOX15TDP1
SCHEMBL6510628 0.75 IDO1 (0.51) ALDH1A1HSD17B10HPGDALOX15MAPT
SCHEMBL6512115 0.74 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDALOX15TDP1
SCHEMBL57324 0.72 ALDH1A1 (0.50) ALDH1A1HSD17B10HPGDALOX15TDP1
SCHEMBL7772549 0.72 ALDH1A1 (0.50) ALDH1A1HSD17B10HPGDALOX15TDP1
SCHEMBL15674713 0.72 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDALOX15TDP1
SCHEMBL11130681 0.71 ALDH1A1 (0.53) ALDH1A1HSD17B10HPGDALOX15TDP1
SCHEMBL15274963 0.71 ALDH1A1 (0.53) ALDH1A1HSD17B10HPGDALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0834304-B1 Use of liposomogenic UV absorbers to protect hair CIBA SC HOLDING AG (CH) 2005-01-26 EP disclosed
EP-0815071-B1 LIPOSOMOGENIC UV ABSORBERS CIBA SC HOLDING AG (CH) 2001-04-11 EP disclosed
US-6017556-A PROTECTING HUMAN HAIR FROM THE DAMAGING EFFECT OF ULTRAVIOLET RADIATION BY TREATING HUMAN HAIR WITH A LIPOSOMOGENIC ULTRAVIOLET RADIATION ABSORBER CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-01-25 US disclosed
US-6015575-A TRIAZINE, BENZOTRIAZOLE, BENZOPHENONE AND AMINOBENZOIC ACID DERIVATIVES AS RADIATION ABSORBERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-01-18 US disclosed
EP-0468921-B2 Aqueous dispersions of slightly soluble UV absorbing agents CIBA GEIGY AG (CH) 1998-07-22 EP disclosed
EP-0834304-A2 Liposomogenic UV absorbers Ciba SC Holding AG (CH) 1998-04-08 EP disclosed
EP-0815071-A1 LIPOSOMOGENIC UV ABSORBERS Ciba SC Holding AG (CH) 1998-01-07 EP disclosed
US-5575958-A HYDROXYPHENYL TRIAZINES CIBA-GEIGY CORPORATION (US) 1996-11-19 US disclosed
WO-1996029302-A1 LIPOSOMOGENIC UV ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-09-26 WO disclosed
EP-0523006-B1 Process for printing and photochemically stabilizing polyester fibre materials CIBA GEIGY AG (CH) 1995-11-29 EP disclosed
EP-0523006-A1 Process for printing and photochemically stabilizing polyester fibre materials CIBA-GEIGY AG (CH) 1993-01-13 EP disclosed
EP-0280653-B1 PROCESS FOR IMPROVING THE PHOTOCHEMICAL STABILITY OF DYEINGS ON FIBROUS POLYESTER MATERIALS CIBA-GEIGY AG (CH) 1992-05-13 EP disclosed
EP-0468921-A1 Aqueous dispersions of slightly soluble UV absorbing agents CIBA-GEIGY AG (CH) 1992-01-29 EP disclosed
US-4831068-A PHENYL-S-TRIAZINE DERIVATIVES AS UV ABSORBERS CIBA-GEIGY CORPORATION (US) 1989-05-16 US disclosed