SCHEMBL6511484

SCHEMBL6511484

Cc1ccc(O)c(-c2nc(C)nc(C)n2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
IDO1 P14902 1/20 0.47
TRPA1 O75762 1/20 0.46
CYP19A1 P11511 1/20 0.45
TDP1 Q9NUW8 3/20 0.45
TP53 P04637 2/20 0.45
HSD17B10 Q99714 4/20 0.45
HPGD P15428 5/20 0.44
ALOX15 P16050 4/20 0.44
MAPT P10636 4/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
LMNA P02545 2/20 0.44
GAA P10253 2/20 0.44
USP2 O75604 2/20 0.44
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.44
NPC1 O15118 3/20 0.43
F2 P00734 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12714307 0.90 TRPA1 (0.52) ALDH1A1IDO1TRPA1CYP19A1TDP1
SCHEMBL6510628 0.81 IDO1 (0.51) ALDH1A1SMN1; SMN2IDO1CYP19A1HSD17B10
SCHEMBL5069137 0.81 NPC1 (0.68) ALDH1A1SMN1; SMN2IDO1TRPA1CYP19A1
SCHEMBL9444924 0.79 IDO1 (0.44) ALDH1A1IDO1TRPA1CYP19A1TDP1
SCHEMBL6512115 0.79 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2TDP1TP53HSD17B10
SCHEMBL26232916 0.79 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2TDP1TP53HSD17B10
SCHEMBL9444864 0.78 NPC1 (0.47) ALDH1A1IDO1TRPA1CYP19A1TDP1
SCHEMBL6510644 0.78 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2TDP1HSD17B10HPGD
SCHEMBL9487748 0.78 CYP1A2 (0.58) ALDH1A1SMN1; SMN2IDO1CYP19A1TDP1
SCHEMBL29763149 0.78 TRPA1 (0.65) ALDH1A1IDO1TRPA1CYP19A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0834304-B1 Use of liposomogenic UV absorbers to protect hair CIBA SC HOLDING AG (CH) 2005-01-26 EP disclosed
EP-0815071-B1 LIPOSOMOGENIC UV ABSORBERS CIBA SC HOLDING AG (CH) 2001-04-11 EP disclosed
US-6017556-A PROTECTING HUMAN HAIR FROM THE DAMAGING EFFECT OF ULTRAVIOLET RADIATION BY TREATING HUMAN HAIR WITH A LIPOSOMOGENIC ULTRAVIOLET RADIATION ABSORBER CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-01-25 US disclosed
US-6015575-A TRIAZINE, BENZOTRIAZOLE, BENZOPHENONE AND AMINOBENZOIC ACID DERIVATIVES AS RADIATION ABSORBERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-01-18 US disclosed
EP-0468921-B2 Aqueous dispersions of slightly soluble UV absorbing agents CIBA GEIGY AG (CH) 1998-07-22 EP disclosed
EP-0834304-A2 Liposomogenic UV absorbers Ciba SC Holding AG (CH) 1998-04-08 EP disclosed
US-5575958-A HYDROXYPHENYL TRIAZINES CIBA-GEIGY CORPORATION (US) 1996-11-19 US disclosed
EP-0523006-B1 Process for printing and photochemically stabilizing polyester fibre materials CIBA GEIGY AG (CH) 1995-11-29 EP disclosed
EP-0523006-A1 Process for printing and photochemically stabilizing polyester fibre materials CIBA-GEIGY AG (CH) 1993-01-13 EP disclosed
EP-0280653-B1 PROCESS FOR IMPROVING THE PHOTOCHEMICAL STABILITY OF DYEINGS ON FIBROUS POLYESTER MATERIALS CIBA-GEIGY AG (CH) 1992-05-13 EP disclosed
EP-0468921-A1 Aqueous dispersions of slightly soluble UV absorbing agents CIBA-GEIGY AG (CH) 1992-01-29 EP disclosed
US-4831068-A PHENYL-S-TRIAZINE DERIVATIVES AS UV ABSORBERS CIBA-GEIGY CORPORATION (US) 1989-05-16 US disclosed