Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL555003 | 0.88 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL22288214 | 0.85 | ALDH1A1 (0.48) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL30834684 | 0.83 | BTN3A1 (0.38) | ALDH1A1CYP3A4 | |
| SCHEMBL28444899 | 0.80 | ALDH1A1 (0.38) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL2773549 | 0.78 | CYP3A4 (0.39) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL3951366 | 0.78 | TSHR (0.35) | ALDH1A1TSHR | |
| SCHEMBL6014558 | 0.76 | TSHR (0.65) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL29212840 | 0.76 | TSHR (0.65) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL30902591 | 0.76 | CYP3A4 (0.54) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL3175341 | 0.74 | ALDH1A1 (0.33) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050010041-A1 | Bacterial gene and method of treating a gram negative bacterial infection | UNIVERSITY OF GUELPH (CA) | 2005-01-13 | — | — | US | disclosed |
| US-6570006-B1 | Nucleotide sequences coding polypeptide for use in the treatment and prevention of bacterial infections | UNIVERSITY OF GUELPH (CA) | 2003-05-27 | — | — | US | disclosed |
| WO-1999066049-A2 | A NOVEL GENE AND METHOD OF TREATING A GRAM NEGATIVE BACTERIAL INFECTION | UNIVERSITY OF GUELPH (CA) | 1999-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050010041-A1 | Bacterial gene and method of treating a gram negative bacterial infection | WAPL, BPGM, MGAM | ALDH1A1 3442/4885CYP3A4 4426/4885TSHR 4694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.