Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 16/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507548 | 0.85 | ROCK2 (0.53) | ROCK2ROCK1HDAC6 | |
| SCHEMBL7608380 | 0.85 | ROCK2 (0.53) | ROCK2ROCK1HDAC6 | |
| SCHEMBL7604788 | 0.85 | ROCK2 (0.53) | ROCK2ROCK1HDAC6 | |
| SCHEMBL7819700 | 0.81 | ROCK2 (0.46) | ROCK2ROCK1 | |
| SCHEMBL19513366 | 0.79 | HDAC1 (0.58) | HDAC6HDAC1HDAC8 | |
| SCHEMBL19513372 | 0.79 | HDAC1 (0.58) | HDAC6HDAC1HDAC8 | |
| SCHEMBL6508427 | 0.77 | CA12 (0.62) | HDAC6HDAC1HDAC8 | |
| SCHEMBL6508236 | 0.77 | ROCK2 (0.38) | ROCK2ROCK1 | |
| SCHEMBL21419972 | 0.76 | ROCK2 (0.75) | ROCK2ROCK1 | |
| SCHEMBL8788443 | 0.74 | CA12 (0.43) | ROCK2HDAC6HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000824-A1 | LAZOLIDINE DERIVATIVES AS HERBICIDAL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-06 | — | — | WO | disclosed |
| CN-1322195-A | Substituted pyrroldinone, thizolidinone or oxazolidinone as herbicides | ZENECA LTD (GB) | 2001-11-14 | — | — | CN | disclosed |
| EP-1119547-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | Syngenta Limited (GB) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000021928-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2000-04-20 | — | — | WO | disclosed |
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |