Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507723 | 0.85 | DRD2 (0.42) | ROCK2HCRTR1HCRTR2 | |
| SCHEMBL8096256 | 0.81 | ROCK2 (0.39) | ROCK2HCRTR1HCRTR2KMT2ATOP2A | |
| SCHEMBL6508760 | 0.78 | CA12 (0.45) | KMT2AALDH1A1 | |
| SCHEMBL6510658 | 0.77 | ROCK2 (0.53) | ROCK2ROCK1 | |
| SCHEMBL8885582 | 0.73 | DRD2 (0.42) | ROCK2HCRTR1HCRTR2RXRAGRIN1 | |
| SCHEMBL8666490 | 0.72 | KMT2A (0.35) | ROCK2HCRTR1KMT2ATOP2AALDH1A1 | |
| SCHEMBL6512656 | 0.71 | CYP1A2 (0.44) | KMT2AALDH1A1 | |
| SCHEMBL9267232 | 0.71 | LIPE (0.46) | — | |
| SCHEMBL8554346 | 0.69 | MCHR1 (0.40) | — | |
| SCHEMBL8662936 | 0.69 | MCHR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000824-A1 | LAZOLIDINE DERIVATIVES AS HERBICIDAL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-06 | — | — | WO | disclosed |