Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4928113 | 0.81 | HPGD (0.55) | HPGDKMT2AHDAC1ALDH1A1PTGS2 | |
| SCHEMBL6511520 | 0.79 | POLB (0.57) | HPGDCYP1A2CYP2C19KMT2AALDH1A1 | |
| SCHEMBL6511156 | 0.75 | POLB (0.51) | HDAC1HDAC3CSNK2A2KDRCSNK2B | |
| SCHEMBL6513961 | 0.75 | USP2 (0.54) | HPGDKMT2AALDH1A1POLBPLK1 | |
| SCHEMBL4932450 | 0.72 | ROCK1 (0.55) | HPGDCYP3A4KMT2AHDAC1ALDH1A1 | |
| SCHEMBL4927332 | 0.72 | HPGD (0.65) | ACKR3HPGDKMT2AHDAC1ALDH1A1 | |
| SCHEMBL6511511 | 0.71 | POLB (0.54) | HPGDCYP1A2KMT2AALDH1A1POLB | |
| SCHEMBL425495 | 0.71 | MMP12 (0.58) | HPGDKMT2AHDAC1ALDH1A1PTGS2 | |
| SCHEMBL21296309 | 0.70 | HPGD (0.63) | HPGDCYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL7713793 | 0.70 | ALOX5 (0.73) | HPGDCYP3A4CYP2C19KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082899-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2005-09-09 | — | — | WO | disclosed |