Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 7/20 | 0.53 |
| ▸ | HTR2B | P41595 | 5/20 | 0.53 |
| ▸ | HTR2A | P28223 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513706 | 0.91 | GID4 (0.59) | KDM4ERAB9ANPC1PKMGID4 | |
| SCHEMBL6510966 | 0.88 | HTR2C (0.54) | KDM4ERAB9ANPC1PKMGID4 | |
| SCHEMBL6514406 | 0.88 | HTR2C (0.54) | KDM4ERAB9ANPC1PKMGID4 | |
| SCHEMBL20510494 | 0.86 | HTR2C (0.71) | KDM4EGID4HTR2CHTR2BHTR2A | |
| SCHEMBL6507699 | 0.86 | KMT2A (0.57) | KDM4EGID4HTR2CHTR2BHTR2A | |
| SCHEMBL6511728 | 0.84 | HTR2C (0.57) | KDM4EGID4HTR2CHTR2BHTR2A | |
| SCHEMBL6511884 | 0.84 | HTR2C (0.57) | KDM4EGID4HTR2CHTR2BHTR2A | |
| Trifluoroacetic Acid SCHEMBL20510471 | 0.82 | HTR2C (0.65) | KDM4EGID4HTR2CHTR2BHTR2A | |
| SCHEMBL20510457 | 0.79 | HTR2C (0.69) | KDM4EGID4HTR2CHTR2BHTR2A | |
| SCHEMBL20510514 | 0.78 | HTR2C (0.69) | KDM4EGID4HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040108-A1 | PROLINAMIDE DERIVATIVES AS SODIUM AND/OR CALCIUM CHANNEL BLOCKERS OR SELECTIVE MAO-B INHIBITORS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-05-06 | — | — | WO | claimed |
| WO-2005040108-A1 | PROLINAMIDE DERIVATIVES AS SODIUM AND/OR CALCIUM CHANNEL BLOCKERS OR SELECTIVE MAO-B INHIBITORS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-05-06 | — | — | WO | disclosed |