Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 9/20 | 0.57 |
| ▸ | HTR2B | P41595 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510966 | 0.92 | HTR2C (0.54) | GID4HTR2CHTR2BKDM4EHTR2A | |
| SCHEMBL6514406 | 0.92 | HTR2C (0.54) | GID4HTR2CHTR2BKDM4EHTR2A | |
| SCHEMBL6511004 | 0.91 | KDM4E (0.68) | GID4HTR2CHTR2BKDM4EHTR2A | |
| SCHEMBL20510494 | 0.84 | HTR2C (0.71) | GID4HTR2CHTR2BKDM4EHTR2A | |
| SCHEMBL6507699 | 0.80 | KMT2A (0.57) | GID4HTR2CHTR2BKDM4EHTR2A | |
| Trifluoroacetic Acid SCHEMBL20510471 | 0.80 | HTR2C (0.65) | GID4HTR2CHTR2BKDM4EHTR2A | |
| SCHEMBL6511884 | 0.79 | HTR2C (0.57) | GID4HTR2CHTR2BKDM4EHTR2A | |
| SCHEMBL6511728 | 0.79 | HTR2C (0.57) | GID4HTR2CHTR2BKDM4EHTR2A | |
| SCHEMBL20510457 | 0.77 | HTR2C (0.69) | GID4HTR2CHTR2BKDM4EHTR2A | |
| SCHEMBL6510397 | 0.77 | HTR2C (0.58) | GID4HTR2CHTR2BKDM4EHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040108-A1 | PROLINAMIDE DERIVATIVES AS SODIUM AND/OR CALCIUM CHANNEL BLOCKERS OR SELECTIVE MAO-B INHIBITORS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-05-06 | — | — | WO | claimed |
| WO-2005040108-A1 | PROLINAMIDE DERIVATIVES AS SODIUM AND/OR CALCIUM CHANNEL BLOCKERS OR SELECTIVE MAO-B INHIBITORS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-05-06 | — | — | WO | disclosed |