Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | CDK9 | P50750 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27841702 | 0.86 | MAOA (0.61) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL18457048 | 0.86 | CES2 (0.62) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL31338553 | 0.86 | NPC1 (0.82) | NPC1RAB9AKMT2ALMNAMEN1 | |
| SCHEMBL27822577 | 0.86 | CES2 (0.62) | NPC1RAB9AKMT2ALMNAMEN1 | |
| SCHEMBL11654888 | 0.84 | KMT2A (0.51) | NPC1RAB9AKMT2ALMNAMEN1 | |
| Benzene SCHEMBL28977956 | 0.83 | SMN1; SMN2 (0.70) | NPC1RAB9AKMT2ALMNAMEN1 | |
| SCHEMBL57554 | 0.83 | SMN1; SMN2 (0.70) | NPC1RAB9AKMT2ALMNAMEN1 | |
| SCHEMBL27822575 | 0.82 | NPC1 (0.50) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL27841707 | 0.82 | NPC1 (0.71) | NPC1RAB9AKMT2ALMNAMEN1 | |
| SCHEMBL31338544 | 0.82 | RAB9A (0.71) | NPC1RAB9AKMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019336-A | 4-Hydroxy-5-phenylaminoimidazole compound, and preparation method and application thereof | 浙大城市学院 | 2024-11-26 | — | — | CN | disclosed |
| WO-2005066151-A2 | HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2005-07-21 | — | — | WO | disclosed |
| US-5556998-A | Transition metal complex, process for the preparation of the same, and asymmetric hydrogenation catalyst comprising the same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0025842-B1 | PEPTIDES, PROCESS FOR THEIR PREPARATION, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR INTERMEDIATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-03 | — | — | EP | disclosed |