Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 13/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 13/20 | 0.46 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.45 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | CTSA | P10619 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512395 | 0.89 | ITGB1 (0.49) | ITGB1ITGA4KMT2A | |
| SCHEMBL6513196 | 0.78 | ITGB1 (0.53) | ITGB1ITGA4KMT2A | |
| SCHEMBL6515884 | 0.78 | ITGB3 (0.46) | ITGB1ITGA4JAK2CYP3A4JAK1 | |
| SCHEMBL6529457 | 0.77 | SMN1; SMN2 (0.59) | ITGB1ITGA4ITGA2ITGB7GAA | |
| SCHEMBL6511921 | 0.75 | KMT2A (0.53) | ITGB1ITGA4ITGA2ITGB7TAS1R3 | |
| SCHEMBL6509549 | 0.75 | ITGB1 (0.63) | ITGB1ITGA4CTSA | |
| SCHEMBL6518236 | 0.72 | ITGB1 (0.52) | ITGB1ITGA4RAB9ACTSA | |
| SCHEMBL6509698 | 0.72 | ITGB1 (0.48) | ITGB1ITGA4RAB9AITGB3ITGA2B | |
| SCHEMBL6513291 | 0.72 | ITGB1 (0.48) | ITGB1ITGA4RAB9ACYP3A4KMT2A | |
| SCHEMBL6512380 | 0.71 | ITGA4 (0.50) | ITGB1ITGA4JAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953798-B1 | β-alanine derivates | CELLTECH R&D LIMITED (GB) | 2005-10-11 | — | — | US | disclosed |