Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532417 | 0.91 | ALDH1A1 (0.43) | FFAR1FFAR4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6511174 | 0.90 | FFAR1 (0.43) | FFAR1FFAR4PPARGNPC1RAB9A | |
| SCHEMBL6511970 | 0.89 | ALDH1A1 (0.42) | ALDH1A1HPGDHSD17B10RAB9APLK1 | |
| SCHEMBL6510333 | 0.87 | PLK1 (0.46) | ALDH1A1PLK1S1PR1S1PR3S1PR2 | |
| SCHEMBL6511699 | 0.87 | FFAR1 (0.43) | FFAR1FFAR4ALDH1A1PPARGNPC1 | |
| SCHEMBL6511036 | 0.86 | PPARA (0.42) | FFAR1FFAR4ALDH1A1PPARGNPC1 | |
| SCHEMBL6515022 | 0.85 | PLK1 (0.44) | ALDH1A1PLK1S1PR1S1PR3S1PR2 | |
| SCHEMBL6509250 | 0.81 | CSF1R (0.39) | FFAR4PPARGNPC1RAB9A | |
| SCHEMBL6510345 | 0.80 | HDAC3 (0.49) | FFAR1FFAR4 | |
| SCHEMBL6532562 | 0.79 | THRB (0.38) | FFAR1FFAR4ALDH1A1HPGDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |