Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509334 | 0.99 | PPARA (0.46) | PPARAPPARGS1PR1S1PR3S1PR2 | |
| SCHEMBL6508452 | 0.95 | NPC1 (0.44) | PPARAPPARGTHRATHRBHDAC3 | |
| SCHEMBL6509203 | 0.89 | PPARA (0.48) | PPARAPPARGS1PR1S1PR3S1PR2 | |
| SCHEMBL6511036 | 0.88 | PPARA (0.42) | PPARAPPARGS1PR1S1PR3S1PR2 | |
| SCHEMBL6531857 | 0.88 | PPARA (0.42) | PPARAPPARGS1PR1S1PR3S1PR2 | |
| SCHEMBL6510672 | 0.87 | RAB9A (0.42) | PPARAPPARGS1PR1 | |
| SCHEMBL6511699 | 0.87 | FFAR1 (0.43) | PPARAPPARGS1PR1THRB | |
| SCHEMBL6509240 | 0.85 | PPARA (0.41) | PPARAPPARGS1PR1S1PR3S1PR2 | |
| SCHEMBL6509250 | 0.85 | CSF1R (0.39) | PPARAPPARGCSF1R | |
| SCHEMBL6511867 | 0.85 | HDAC3 (0.47) | PPARAPPARGHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |