Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 4/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509451 | 0.92 | NR1H3 (0.41) | NR1H3FFAR1MEP1B | |
| SCHEMBL6516293 | 0.91 | NR1H2 (0.42) | NR1H3NR1H2FFAR1MEN1KMT2A | |
| SCHEMBL6511846 | 0.89 | FFAR1 (0.44) | FFAR1MEN1KMT2APTGESMEP1B | |
| SCHEMBL6509514 | 0.86 | NR1H3 (0.40) | NR1H3NR1H2FFAR1GPR88PTGES | |
| SCHEMBL6512310 | 0.84 | PTGES (0.43) | NR1H3NR1H2FFAR1PTGESMEP1B | |
| SCHEMBL6512693 | 0.84 | TSHR (0.49) | FFAR1PTGES | |
| SCHEMBL6515073 | 0.84 | PLA2G4B (0.47) | NR1H3MEP1B | |
| SCHEMBL6507826 | 0.84 | FOS (0.43) | NR1H3NR1H2FFAR1PTGESMEP1B | |
| SCHEMBL6510769 | 0.82 | PTGES (0.38) | FFAR1GPR88MEN1KMT2APTGES | |
| SCHEMBL6511170 | 0.82 | FFAR1 (0.40) | NR1H3NR1H2FFAR1MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |