Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 4/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509306 | 0.92 | NR1H3 (0.40) | NR1H3MEP1BFFAR1BCHE | |
| SCHEMBL6518975 | 0.92 | FFAR1 (0.43) | NR1H3PTGESMEP1BFFAR1PPARD | |
| SCHEMBL6515031 | 0.87 | MEP1B (0.43) | NR1H3MEP1B | |
| SCHEMBL6511974 | 0.86 | NR1H3 (0.41) | NR1H3NR1H2GPR88PTGESMEP1B | |
| SCHEMBL6511147 | 0.85 | TSHR (0.47) | PTGESFFAR1 | |
| SCHEMBL6511846 | 0.85 | FFAR1 (0.44) | PTGESMEP1BFFAR1BCHE | |
| SCHEMBL6508932 | 0.84 | FFAR1 (0.42) | NR1H3NR1H2PTGESFFAR1PPARD | |
| SCHEMBL6512310 | 0.83 | PTGES (0.43) | NR1H3NR1H2PTGESMEP1BFFAR1 | |
| SCHEMBL6531896 | 0.82 | FFAR4 (0.48) | FFAR1PPARD | |
| SCHEMBL6531593 | 0.81 | FFAR4 (0.47) | FFAR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |