Sugi Predict

Sugi Predict / Compounds / Norflurazone

Norflurazone

Norflurazone

SCHEMBL6512279

CNc1cnn(-c2cccc(C(F)(F)F)c2)c(=O)c1Cl.CNc1cnn(-c2cccc(C(F)(F)F)c2)c(=O)c1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 2/20 0.66
▸ CYP2C9 P11712 1/20 0.66
▸ HTT P42858 1/20 0.66
▸ RAB9A P51151 7/20 0.57
▸ NPC1 O15118 5/20 0.57
▸ SMN1; SMN2 Q16637 4/20 0.57
▸ NPBWR1 P48145 1/20 0.55
▸ MCHR1 Q99705 1/20 0.55
▸ KMT2A Q03164 2/20 0.50
▸ PKM P14618 1/20 0.50
▸ PAX8 Q06710 1/20 0.48
▸ MAPT P10636 2/20 0.46
▸ HPGD P15428 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ GAA P10253 1/20 0.46
▸ KAT2B Q92831 1/20 0.46
▸ BRD9 Q9H8M2 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ MAT2A P31153 1/20 0.45
▸ CYP3A4 P08684 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Norflurazone SCHEMBL54676 1.00 CYP1A2 (0.66) CYP1A2CYP2C9HTTRAB9ANPC1
Norflurazone SCHEMBL29776940 1.00 CYP1A2 (0.66) CYP1A2CYP2C9HTTRAB9ANPC1
Norflurazone SCHEMBL7039956 0.99 CYP1A2 (0.64) CYP1A2CYP2C9HTTRAB9ANPC1
Norflurazone SCHEMBL28530944 0.99 CYP1A2 (0.64) CYP1A2CYP2C9HTTRAB9ANPC1
Norflurazone SCHEMBL27382340 0.93 CYP1A2 (0.61) CYP1A2CYP2C9HTTRAB9ANPC1
Norflurazone SCHEMBL28173162 0.93 CYP1A2 (0.61) CYP1A2CYP2C9HTTRAB9ANPC1
Norflurazone SCHEMBL22721303 0.92 CYP1A2 (0.56) CYP1A2CYP2C9HTTRAB9ANPC1
Norflurazone SCHEMBL10870860 0.91 CYP1A2 (0.64) CYP1A2CYP2C9HTTRAB9ANPC1
SCHEMBL27569421 0.89 HTT (0.67) CYP1A2CYP2C9HTTRAB9ANPC1
Norflurazone SCHEMBL27357023 0.88 CYP1A2 (0.52) CYP1A2CYP2C9HTTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050142113-A1 Antimicrobial agents, diagnostic reagents, and vaccines based on unique apicomplexan parasite components MCLEOD RIMA I (US) 2005-06-30 — — US disclosed
EP-0574418-B1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-11-11 — — EP disclosed
US-5688745-A Arylsulfonylureas and their use as herbicides and growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-18 — — US disclosed
US-5463081-A Chemical intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-31 — — US disclosed
EP-0574418-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1993-12-22 — — EP disclosed
EP-0548264-A1 HERBICIDAL SUBSTITUTED BICYCLIC TRIAZOLES. DU PONT (US) 1993-06-30 — — EP disclosed
EP-0546082-A1 HERBICIDAL PYRROLESULFONYLUREAS. DU PONT (US) 1993-06-16 — — EP disclosed
WO-1992013845-A1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-20 — — WO disclosed
WO-1992013861-A1 HERBICIDAL BICYCLIC ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-08-20 — — WO disclosed
WO-1992010501-A1 HERBICIDAL ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-06-25 — — WO disclosed
WO-1992004827-A1 HERBICIDAL SUBSTITUTED BICYCLIC TRIAZOLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-02 — — WO disclosed
EP-0463054-A1 SELECTIVE OXABICYCLOALKANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-02 — — EP disclosed
EP-0457802-A1 HERBICIDAL OXABICYCLONONANE ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-11-27 — — EP disclosed
WO-1991015478-A1 CROP-SELECTIVE HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-17 — — WO disclosed
WO-1991010653-A1 HERBICIDAL PYRIMIDINES AND TRIAZINES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-25 — — WO disclosed
WO-1991010668-A1 HERBICIDAL SULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-25 — — WO disclosed
WO-1991003464-A1 HERBICIDAL OXABICYCLO ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-21 — — WO disclosed
WO-1990012012-A1 SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-18 — — WO disclosed
WO-1990010634-A1 SELECTIVE OXABICYCLOALKANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-20 — — WO disclosed
WO-1990009383-A1 HERBICIDAL OXABICYCLONONANE ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050142113-A1 Antimicrobial agents, diagnostic reagents, and vaccines based on unique apicomplexan parasite components POLRMT, PCK1, PSAT1 CYP1A2 4456/4885CYP2C9 3810/4885HTT 3169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.