Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | ESRRB | O95718 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8535929 | 0.83 | KCNA5 (0.49) | KCNA5KMT2ATSHRPGRADRA2A | |
| SCHEMBL5509777 | 0.82 | PGR (0.49) | KMT2ATSHRPGRADRA2AADRA2B | |
| SCHEMBL22076551 | 0.79 | KMT2A (0.49) | KCNA5KMT2ATSHRPGRADRA2A | |
| SCHEMBL9714993 | 0.78 | KMT2A (0.47) | KCNA5KMT2ATSHRPGRADRA2A | |
| SCHEMBL4092391 | 0.78 | KCNA5 (0.48) | KCNA5KMT2ATSHRPGRADRA2A | |
| SCHEMBL16624926 | 0.78 | KCNA5 (0.58) | KCNA5KMT2ATSHR | |
| SCHEMBL8882153 | 0.77 | PGR (0.55) | KMT2APGRADRA2AADRA2BHTR2A | |
| SCHEMBL1427972 | 0.77 | MDM2 (0.47) | KCNA5KMT2ATSHRPGRADRA2A | |
| SCHEMBL5522123 | 0.76 | KCNA5 (0.64) | KCNA5KMT2AMAPTRAB9A | |
| SCHEMBL9909376 | 0.76 | KCNA5 (0.64) | KCNA5KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005035497-A1 | CASPASE INHIBITOR COMPRISING 2-ALKYL-4-OXOBUTANOYL GROUP AND PHARMACEUTICAL COMPOSITION THEREOF | LG LIFE SCIENCES LTD. (KR) | 2005-04-21 | — | — | WO | disclosed |