Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GALR3 | O60755 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4252480 | 0.79 | CHRM1 (0.45) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| SCHEMBL4783813 | 0.77 | CHRM1 (0.59) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| Bromide SCHEMBL8759877 | 0.77 | CHRM1 (0.43) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| Hydrochloric Acid SCHEMBL16637634 | 0.77 | MAPT (0.47) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| Iodide SCHEMBL27443982 | 0.76 | CHRM1 (0.57) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| SCHEMBL27607678 | 0.76 | CHRM2 (0.42) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| Hydrochloric Acid SCHEMBL28364686 | 0.76 | MAPT (0.61) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| Hydrochloric Acid SCHEMBL10633363 | 0.76 | MAPT (0.61) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| SCHEMBL28114484 | 0.72 | MEN1 (0.51) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| Phosphoric Acid SCHEMBL29285420 | 0.71 | CHRM1 (0.52) | CHRM1CHRM2CHRM4TSHRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105343191-B | Application of the Jasminum nervosum Lour extract in preparation acetylcholinesterase inhibitor | 广西中医药大学 | 2019-06-07 | — | — | CN | disclosed |
| CN-106905317-B | 4- replaces Sampangine alcaloid-derivatives and its synthetic method and application | 广西师范大学 | 2019-03-22 | — | — | CN | disclosed |
| CN-109456328-A | 11- replaces 1,6- diaza benzo anthracyclinone derivatives and its synthetic method and application | 广西师范大学 | 2019-03-12 | — | — | CN | disclosed |
| CN-109438445-A | 8- replaces 1,6- diaza benzo anthracyclinone derivatives and its synthetic method and application | 广西师范大学 | 2019-03-08 | — | — | CN | disclosed |
| CN-107513084-A | White crane rattan alkali and its extracting method and application thereof | 广西中医药大学 | 2017-12-26 | — | — | CN | disclosed |
| CN-106038564-A | Application of 11-substituted oxoisoaporphine derivatives | 广西师范大学 | 2016-10-26 | — | — | CN | disclosed |
| CN-105998022-A | Application of 8-substituted oxoisoaporphine derivatives | 广西师范大学 | 2016-10-12 | — | — | CN | disclosed |
| CN-104327075-B | A kind of 9-amino substituted pyridines Acridine derivatives and its production and use | 广西中医药大学 | 2016-08-24 | — | — | CN | disclosed |
| CN-103923009-B | 8-replaces the different aporphine derivative of oxidation and synthetic method and application | GUANGXI NORMAL UNIVERSITY (CN) | 2016-03-23 | — | — | CN | disclosed |
| CN-103923010-B | 11-replaces the different aporphine derivative of oxidation and synthetic method and application | GUANGXI NORMAL UNIVERSITY (CN) | 2016-03-23 | — | — | CN | disclosed |
| CN-103923009-A | 8-substitued oxoisoaporphine derivatives as well as synthetic method and application thereof | UNIV GUANGXI NORMAL | 2014-07-16 | — | — | CN | disclosed |
| CN-103923010-A | 11-replaced oxoisoaporphine derivatives as well as synthetic method and application thereof | UNIV GUANGXI NORMAL | 2014-07-16 | — | — | CN | disclosed |
| CN-102408395-A | Novel piperazine and homopiperazine derivatives, preparation method and application thereof | UNIV GUANGXI NORMAL | 2012-04-11 | — | — | CN | disclosed |
| CN-101597294-B | 3-aminoalkaneacylamino-rutaecarpine and 3-aminoalkaneacylamino-7,8-dehydrorutaecarpine derivative | UNIV SUN YAT SEN | 2011-09-07 | — | — | CN | disclosed |
| CN-101575341-B | Amidocyanogen amido xanthone pyridine derivant, and preparation method and application thereof | UNIV GUANGXI NORMAL | 2011-04-27 | — | — | CN | disclosed |
| CN-101020659-B | 9-aminoalkylamido-1-azabenznthrone derivative and its synthesis and application | UNIV SUN YAT SEN | 2010-06-23 | — | — | CN | disclosed |
| CN-101597294-A | 3-amidocyanogen amido-Rutaecarpine and 3-amidocyanogen amido-7,8-dehydrogenation Rutaecarpine derivative | UNIV SUN YAT SEN (CN) | 2009-12-09 | — | — | CN | disclosed |
| CN-101575341-A | Amidocyanogen amido xanthone pyridine derivant, and preparation method and application thereof | UNIV GUANGXI NORMAL (CN) | 2009-11-11 | — | — | CN | disclosed |
| CN-101020659-A | 9-aminoalkylamido-1-azabenznthrone derivative and its synthesis and application | UNIV SUN YAT SEN (CN) | 2007-08-22 | — | — | CN | disclosed |
| US-20050176118-A1 | Esterases with lipase activity | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2005-08-11 | — | — | US | disclosed |