Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GALR3 | O60755 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16637634 | 0.98 | MAPT (0.47) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| Bromide SCHEMBL8759877 | 0.98 | CHRM1 (0.43) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| Methacholine SCHEMBL1536636 | 0.85 | TSHR (0.72) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| SCHEMBL4783813 | 0.79 | CHRM1 (0.59) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| SCHEMBL27362812 | 0.79 | LMNA (0.47) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| SCHEMBL6512446 | 0.79 | CHRM1 (0.43) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| Hydrochloric Acid SCHEMBL1759064 | 0.77 | LMNA (0.48) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| Hydrochloric Acid SCHEMBL28364686 | 0.77 | MAPT (0.61) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| Hydrochloric Acid SCHEMBL10633363 | 0.77 | MAPT (0.61) | CHRM1CHRM2CHRM4TSHRTBXA2R | |
| Iodide SCHEMBL27443982 | 0.77 | CHRM1 (0.57) | CHRM1CHRM2CHRM4TSHRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110835614-B | Bifidobacterium lactis GKK2, composition containing same and application of composition in improving allergic asthma | 葡萄王生技股份有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-112891397-A | Compound essential oil preparation for treating asthma and preparation method and application thereof | 江西中医药大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-110835614-A | Bifidobacterium lactis GKK2, composition containing the same and use thereof for improving allergic asthma | 葡萄王生技股份有限公司 | 2020-02-25 | — | — | CN | disclosed |
| EP-3030252-A2 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | Ardelyx, Inc. (US) | 2016-06-15 | — | — | EP | disclosed |
| WO-2015021358-A2 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | CHARMOT DOMINIQUE (US) | 2015-02-12 | — | — | WO | disclosed |
| US-20140086960-A1 | IMMUNOMODULATORY COMPOUNDS AND TREATMENT OF DISEASES RELATED TO AN OVERPRODUCTION OF INFLAMMATORY CYTOKINES | OM PHARMA (CH) | 2014-03-27 | — | — | US | disclosed |
| US-8618080-B2 | Immunomodulatory compounds and treatment of diseases related to an overproduction of inflammatory cytokines | OM PHARMA (CH) | 2013-12-31 | — | — | US | disclosed |
| US-20120178721-A1 | IMMUNOMODULATORY COMPOUNDS AND TREATMENT OF DISEASES RELATED TO AN OVERPRODUCTION OF INFLAMMATORY CYTOKINES | OM PHARMA (CH) | 2012-07-12 | — | — | US | disclosed |
| EP-2051728-A2 | IMMUNOMODULATORY COMPOUNDS AND TREATMENT OF DISEASES RELATED TO AN OVERPRODUCTION OF INFLAMMATORY CYTOKINES | OM Pharma (CH) | 2009-04-29 | — | — | EP | disclosed |
| US-20090054378-A1 | IMMUNOMODULATORY COMPOUNDS AND TREATMENT OF DISEASES RELATED TO AN OVERPRODUCTION OF INFLAMMATORY CYTOKINES | OM PHARMA (CH) | 2009-02-26 | — | — | US | disclosed |
| WO-2007102081-A2 | IMMUNOMODULATORY COMPOUNDS AND TREATMENT OF DISEASES RELATED TO AN OVERPRODUCTION OF INFLAMMATORY CYTOKINES | OM PHARMA (CH) | 2007-09-13 | — | — | WO | disclosed |
| CN-1605349-A | Chinese traditional medicine for treating cough and variable asthma after cold and its preparation | CHAO ENXIANG (CN) | 2005-04-13 | — | — | CN | disclosed |
| WO-2005030245-A1 | INHIBITION OF FRACTALKINE OR OF ITS RECEPTOR FOR THE TREATMENT OF ATOPIC ALLERGIC DISEASES | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2005-04-07 | — | — | WO | disclosed |
| EP-0865419-B1 | INDANE DIMER COMPOUNDS AND THEIR PHARMACEUTICAL USE | VENANTIUS LTD (IE) | 2003-08-06 | — | — | EP | disclosed |
| US-6300376-B1 | FOR THERAPY TO ACHIEVE SMOOTH MUSCLE RELAXING ACTIVITY AND/OR MAST CELL STABILIZING ACTIVITY AND/OR ANTI-INFLAMMATORY ACTIVITY | VENANTIUS LIMITED (IR) | 2001-10-09 | — | — | US | disclosed |
| EP-0865419-A1 | INDANE DIMER COMPOUNDS AND THEIR PHARMACEUTICAL USE | Venantius Limited (IE) | 1998-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054378-A1 | IMMUNOMODULATORY COMPOUNDS AND TREATMENT OF DISEASES RELATED TO AN OVERPRODUCTION OF INFLAMMATORY CYTOKINES | HRH4, HRH2, HRH3 | CHRM1 131/4885CHRM2 125/4885CHRM4 408/4885 |
| US-20140086960-A1 | IMMUNOMODULATORY COMPOUNDS AND TREATMENT OF DISEASES RELATED TO AN OVERPRODUCTION OF INFLAMMATORY CYTOKINES | HRH4, HRH2, IFNG | CHRM1 100/4885CHRM2 109/4885CHRM4 326/4885 |
| US-20120178721-A1 | IMMUNOMODULATORY COMPOUNDS AND TREATMENT OF DISEASES RELATED TO AN OVERPRODUCTION OF INFLAMMATORY CYTOKINES | HRH4, IFNG, HRH2 | CHRM1 86/4885CHRM2 101/4885CHRM4 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.