Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.57 |
| ▸ | CHRM2 known ✓ | P08172 | 3/20 | 0.57 |
| ▸ | CHRM3 known ✓ | P20309 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | GALR3 | O60755 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10633363 | 1.00 | MAPT (0.61) | MAPTSMN1; SMN2GALR3BLMCHRM1 | |
| SCHEMBL4783813 | 0.98 | CHRM1 (0.59) | MAPTSMN1; SMN2GALR3BLMCHRM1 | |
| Iodide SCHEMBL27443982 | 0.96 | CHRM1 (0.57) | MAPTSMN1; SMN2GALR3BLMCHRM1 | |
| Phosphoric Acid SCHEMBL29285420 | 0.90 | CHRM1 (0.52) | MAPTSMN1; SMN2GALR3BLMCHRM1 | |
| Hydrochloric Acid SCHEMBL16637634 | 0.80 | MAPT (0.47) | MAPTSMN1; SMN2GALR3BLMCHRM1 | |
| SCHEMBL28114484 | 0.79 | MEN1 (0.51) | MAPTSMN1; SMN2GALR3BLMCHRM1 | |
| SCHEMBL29613042 | 0.78 | CHRM1 (0.47) | MAPTSMN1; SMN2GALR3BLMCHRM1 | |
| Methacholine SCHEMBL1536636 | 0.77 | TSHR (0.72) | MAPTSMN1; SMN2GALR3BLMCHRM1 | |
| SCHEMBL4252480 | 0.77 | CHRM1 (0.45) | MAPTSMN1; SMN2GALR3BLMCHRM1 | |
| SCHEMBL6512446 | 0.76 | CHRM1 (0.43) | MAPTSMN1; SMN2GALR3BLMCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698355-B | Refining method of succinylcholine chloride | 上海旭东海普药业有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-110698355-A | Refining method of succinylcholine chloride | 上海旭东海普药业有限公司 | 2020-01-17 | — | — | CN | disclosed |