Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.68 |
| ▸ | HTR1A | P08908 | 3/20 | 0.60 |
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | HTR7 | P34969 | 3/20 | 0.60 |
| ▸ | DRD3 | P35462 | 3/20 | 0.60 |
| ▸ | HTR2B | P41595 | 3/20 | 0.60 |
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | HRH1 | P35367 | 2/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24349700 | 0.87 | ABCB1 (0.70) | HRH3HTR1AHTR2AHTR7DRD3 | |
| SCHEMBL1585063 | 0.87 | SLC6A3 (0.61) | HRH3HTR1ADRD3DRD2ACHE | |
| Hydrochloric Acid SCHEMBL7600991 | 0.85 | ABCB1 (0.68) | HRH3HTR1AHTR2AHTR7DRD3 | |
| SCHEMBL16061507 | 0.85 | ABCB1 (0.64) | HTR1AHTR2AHTR7DRD3HTR2B | |
| SCHEMBL28595944 | 0.83 | HRH3 (0.51) | HRH3HTR1AHTR2AHTR7DRD3 | |
| SCHEMBL8491977 | 0.83 | DRD2 (0.59) | HRH3HTR1AHTR2AHTR7DRD3 | |
| SCHEMBL6489547 | 0.83 | ABCB1 (0.53) | HRH3SIGMAR1 | |
| SCHEMBL31174282 | 0.83 | PRMT5 (0.56) | HRH3HTR1AHTR2AHTR7DRD3 | |
| SCHEMBL31134754 | 0.81 | ACHE (0.66) | HTR2BHRH1KDM4EALDH1A1ACHE | |
| SCHEMBL10978742 | 0.81 | ACHE (0.66) | HTR2BHRH1KDM4EALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005077885-A1 | RUTHENIUM-CATALYZED HYDROAMINATION OF OLEFINS | YALE UNIVERSITY (US) | 2005-08-25 | — | — | WO | disclosed |
| WO-1999024022-A2 | ISOQUINOLINE DERIVATIVES FOR TREATING DISORDERS ASSOCIATED WITH 5HT7 RECEPTORS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-05-20 | — | — | WO | disclosed |