SCHEMBL6513384

SCHEMBL6513384

C=[Zr](CCl)(C1=Cc2ccccc2C1C)C1=Cc2ccccc2C1C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 5/20 0.33
DRD4 P21917 5/20 0.33
BRD4 O60885 1/20 0.32
CCL2 P13500 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28895779 0.74 DRD2 (0.41) DRD2DRD4BRD4CCL2
SCHEMBL6514178 0.67 DRD2 (0.36) DRD2DRD4BRD4CCL2
SCHEMBL5475152 0.66 DRD2 (0.40) DRD2DRD4BRD4CCL2
SCHEMBL8854175 0.65 DRD2 (0.39) DRD2DRD4BRD4CCL2
SCHEMBL30177268 0.65 DRD2 (0.39) DRD2DRD4BRD4CCL2
SCHEMBL6719841 0.65 DRD2 (0.39) DRD2DRD4BRD4CCL2
SCHEMBL29458545 0.64 DRD2 (0.41) DRD2DRD4BRD4CCL2
SCHEMBL251288 0.64 DRD2 (0.41) DRD2DRD4BRD4CCL2
SCHEMBL6344924 0.63 DRD2 (0.38) DRD2DRD4BRD4CCL2
Chloromethane SCHEMBL6513380 0.63 DRD2 (0.36) DRD2DRD4BRD4CCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6872863-B2 Methylene bridged metallocenes as olefin-polymerization catalyst components BASELL POLYOLEFINE GMBH (DE) 2005-03-29 US disclosed
US-20040147695-A1 Methylene bridged metallocenes as olefin-polymerization catalyst components BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-07-29 US disclosed
US-6693156-B1 SIMPLY AND EFFICIENTLY SYNTHESIZED MATERIALS WITH VARIED SUBSTITUTION FOR TAILORED POLYMER PROPERTIES BASELL POLYOLEFINE GMBH (DE) 2004-02-17 US disclosed
EP-1131328-B1 METHYLENE BRIDGED METALLOCENES AS OLEFIN-POLYMERIZATION-CATALYST COMPONENTS BASELL POLYOLEFINE GMBH (DE) 2003-05-07 EP disclosed