Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | DRD4 | P21917 | 5/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CCL2 | P13500 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30296975 | 0.75 | HTR2A (0.37) | DRD2CYP11B1CYP11B2RET | |
| SCHEMBL30387247 | 0.75 | DRD2 (0.31) | DRD2DRD4 | |
| SCHEMBL6513384 | 0.74 | DRD2 (0.33) | DRD2DRD4BRD4CCL2 | |
| SCHEMBL29672901 | 0.72 | DRD2 (0.46) | DRD2DRD4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29458545 | 0.71 | DRD2 (0.41) | DRD2DRD4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL251288 | 0.71 | DRD2 (0.41) | DRD2DRD4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL4384850 | 0.71 | DRD2 (0.38) | DRD2DRD4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL5084237 | 0.70 | HTR1A (0.32) | DRD2DRD4 | |
| SCHEMBL5087299 | 0.70 | BRD4 (0.32) | DRD2DRD4BRD4CCL2 | |
| SCHEMBL5475152 | 0.70 | DRD2 (0.40) | DRD2DRD4CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111108130-B | Has the advantages ofcontaining-CH2-SiMe3Hybrid catalysts of partially unbridged hafnocenes | 埃克森美孚化学专利公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-111108130-A | Has the advantages ofcontaining-CH2-SiMe3Hybrid catalysts of partially unbridged hafnocenes | 埃克森美孚化学专利公司 | 2020-05-05 | — | — | CN | disclosed |