Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873528 | 0.84 | PIN1 (0.47) | KMT2AMEN1PIN1NLRP3TSHR | |
| SCHEMBL31257144 | 0.84 | PIN1 (0.47) | KMT2AMEN1PIN1NLRP3TSHR | |
| SCHEMBL6718334 | 0.83 | CA12 (0.49) | KMT2AMAPTPIN1NLRP3TSHR | |
| SCHEMBL31583218 | 0.78 | CASP1 (0.37) | KMT2AMEN1PIN1NLRP3TSHR | |
| SCHEMBL31111234 | 0.78 | PTPN1 (0.42) | MAPK1TDP1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL6529869 | 0.77 | MAPK1 (0.48) | MAPTPIN1NLRP3TSHRMAPK1 | |
| SCHEMBL5379799 | 0.76 | CA1 (0.47) | MAPTNLRP3TSHRMAPK1TDP1 | |
| SCHEMBL490336 | 0.76 | MAPT (0.44) | KMT2AMEN1MAPTTSHRLMNA | |
| SCHEMBL28544218 | 0.76 | ALDH1A1 (0.43) | KMT2AMEN1MAPTNLRP3TSHR | |
| SCHEMBL16960805 | 0.76 | SCN4A (0.33) | KMT2AMEN1MAPTNPSR1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100318-A1 | ALKANOIC ACIDS AND THEIR ESTERS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2005-10-27 | — | — | WO | disclosed |