Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1780660 | 0.97 | MC4R (0.41) | MC4RPAOXLMNASIGMAR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL2966994 | 0.97 | MC4R (0.41) | MC4RPAOXLMNASIGMAR1CYP1A2 | |
| SCHEMBL11570567 | 0.87 | — | — | |
| SCHEMBL7511785 | 0.87 | ALOX15 (0.44) | SIGMAR1ALOX15 | |
| Hydrochloric Acid SCHEMBL29891395 | 0.84 | ALOX15 (0.42) | LMNAALOX15 | |
| SCHEMBL25435212 | 0.84 | HRH3 (0.47) | PAOXSIGMAR1CHKACA2NCF1 | |
| SCHEMBL167231 | 0.83 | PAOX (0.47) | MC4RPAOXSIGMAR1CSNK2A2CSNK2B | |
| SCHEMBL2747507 | 0.81 | PAOX (0.50) | PAOXSIGMAR1CSNK2A2CSNK2BCSNK2A1 | |
| Hydrochloric Acid SCHEMBL409216 | 0.81 | PAOX (0.45) | PAOXSIGMAR1CSNK2A2CSNK2BCSNK2A1 | |
| Hydrochloric Acid SCHEMBL374447 | 0.81 | PAOX (0.45) | PAOXSIGMAR1CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383854-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | HOVIONE FARMACIENCIA SA (PT) | 2024-11-21 | — | — | US | claimed |
| EP-4452952-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | Council of Scientific and Industrial Research, an Indian Registered Body Incorporated under Regn. of Soc. Act (Act XXI of 1860) (IN) | 2024-10-30 | — | — | EP | claimed |
| CN-118451062-A | Preparation and use of quinazolinediones | 科学与工业研究会(按照印度社会团体注册法案(1860年第21号法案)设立的注册机构) | 2024-08-06 | — | — | CN | claimed |
| WO-2023119320-A1 | A PREPARATION OF QUINAZOLINEDIONES AND USE THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2023-06-29 | — | — | WO | claimed |
| CN-109384744-A | The new preparation method of one kind of 1- (2- chloroethyl) -4- methyl piperazine | 南京海燕生物医药科技有限公司 | 2019-02-26 | — | — | CN | claimed |
| EP-0406837-B1 | Cationic polysaccharides and reagents for their preparation | NAT STARCH CHEM INVEST (US) | 1995-10-18 | — | — | EP | claimed |
| CN-115835909-B | Cannabinoid receptor type 2 (CB 2) modulators and uses thereof | 泰昂治疗公司 | 2026-05-15 | — | — | CN | disclosed |
| US-20250326760-A1 | TYK2 INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-10-23 | — | — | US | disclosed |
| US-12404269-B2 | Aminoquinazolinone and aminoisoquinolinone derivatives and application thereof | ZHEJIANG UNIVERSITY (CN) | 2025-09-02 | — | — | US | disclosed |
| CN-119707835-A | 2-Aminopyrimidine-5-carboxamide compounds and use thereof for the production of medicaments for the treatment and/or prophylaxis of cancer | 沈阳药科大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-119192183-A | Benzodiazepines class of compounds and uses thereof | 中国药科大学 | 2024-12-27 | — | — | CN | disclosed |
| US-20240383854-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | HOVIONE FARMACIENCIA SA (PT) | 2024-11-21 | — | — | US | disclosed |
| US-20240376076-A1 | INHIBITORS TARGETING UBIQUITIN SPECIFIC PROTEASE 7 (USP7) | DANA-FARBER CANCER INSTITUTE, INC. | 2024-11-14 | — | — | US | disclosed |
| US-3994902-A | Certain 1,2-diphenyl-1,2,3,4-tetrahydroquinoline compounds | STERLING DRUG INC. (US) | 1976-11-30 | — | — | US | disclosed |
| US-3968121-A | 1,2-Diphenyl-4,5,6,7-tetrahydroindoles | STERLING DRUG INC. (US) | 1976-07-06 | — | — | US | disclosed |
| US-3966736-A | 2,9-Dihydro-3H-pyrido[3,2-c]-s-triazolo[4,3-a][1,5]-benzodiazepin-3-ones | THE UPJOHN COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3960886-A | Substituted N-arylanilines | STERLING DRUG INC. (US) | 1976-06-01 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |
| US-3959272-A | ANALGESICS, ANTIINFLAMMATORY, PSYCHOTROPIC | SOCIETE ANONYME DITE: HEXACHIME (FR) | 1976-05-25 | — | — | US | disclosed |
| US-3935214-A | ANTICOAGULANT | DONAU-PHARMAZIE GESELLSCHAFT M.B.H. (OE) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12404269-B2 | Aminoquinazolinone and aminoisoquinolinone derivatives and application thereof | PIK3R5, PIK3CA, PIK3R1 | MC4R 3796/4885PAOX 2614/4885LMNA 2918/4885 |
| US-20240376076-A1 | INHIBITORS TARGETING UBIQUITIN SPECIFIC PROTEASE 7 (USP7) | USP7, USP47, USP2 | MC4R 4634/4885PAOX 2174/4885LMNA 3340/4885 |
| US-20240383854-A1 | PROCESS FOR THE PREPARATION OF CHLOROALKYL SUBSTITUTED CYCLIC AMINES | ETFB, TOP2B, MGMT | MC4R 4510/4885PAOX 3323/4885LMNA 1506/4885 |
| US-20250326760-A1 | TYK2 INHIBITORS AND USES THEREOF | TYK2, JAK2, JAK1 | MC4R 1684/4885PAOX 1943/4885LMNA 2078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.