Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 19/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16861335 | 0.72 | METAP2 (0.49) | ALPLMAPK1KMT2A | |
| SCHEMBL1413947 | 0.71 | ALPL (1.00) | ALPLALPG | |
| SCHEMBL10682654 | 0.71 | ALPL (0.58) | ALPLMAPK1KMT2AALPG | |
| SCHEMBL6311744 | 0.71 | ALPL (0.62) | ALPLMAPK1KMT2AALPG | |
| SCHEMBL6312493 | 0.71 | ALPL (0.50) | ALPLMAPK1KMT2AALPG | |
| SCHEMBL6510277 | 0.70 | MAPT (0.43) | ALPL | |
| Hydrochloric Acid SCHEMBL15191228 | 0.70 | ALPL (0.56) | ALPLMAPK1KMT2AALPG | |
| SCHEMBL28699820 | 0.70 | ALPL (1.00) | ALPLALPG | |
| SCHEMBL15635608 | 0.69 | GSK3B (0.43) | ALPLMAPK1 | |
| SCHEMBL13539279 | 0.69 | ALPL (0.76) | ALPLALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061507-A1 | BICYCLIC PYRAZOL-4-ONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005061506-A1 | BICYCLIC PYRAZOLYL AND IMIDAZOLYL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005061506-A1 | BICYCLIC PYRAZOLYL AND IMIDAZOLYL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005061507-A1 | BICYCLIC PYRAZOL-4-ONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |