SCHEMBL6514367

SCHEMBL6514367

NCCCCCCCCCCNCCCN

nearest known ligand 0.93

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.93
CA6 P23280 4/20 0.93
CA7 P43166 4/20 0.93
CA9 Q16790 4/20 0.93
CA14 Q9ULX7 4/20 0.93
CA5B Q9Y2D0 4/20 0.93
CA2 P00918 3/20 0.93
CA4 P22748 3/20 0.93
CA5A P35218 3/20 0.93
F13A1 P00488 2/20 0.93
CYP1A2 P05177 2/20 0.93
ALOX15 P16050 2/20 0.93
THPO P40225 2/20 0.93
CA3 P07451 2/20 0.93
CA1 P00915 1/20 0.93
CYP2C9 P11712 1/20 0.93
PKM P14618 1/20 0.93
TSHR P16473 1/20 0.93
MTOR P42345 1/20 0.93
LMNA P02545 1/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1459664 1.00 CA12 (0.93) CA12CA6CA7CA9CA14
SCHEMBL6021973 1.00 CA12 (0.93) CA12CA6CA7CA9CA14
Spermine SCHEMBL28288034 1.00 CA12 (0.93) CA12CA6CA7CA9CA14
SCHEMBL28177765 1.00 CA12 (0.93) CA12CA6CA7CA9CA14
SCHEMBL13741268 1.00 CA12 (0.93) CA12CA6CA7CA9CA14
SCHEMBL818184 1.00 CA12 (0.93) CA12CA6CA7CA9CA14
Spermine SCHEMBL9331554 1.00 CA12 (0.93) CA12CA6CA7CA9CA14
SCHEMBL561079 1.00 CA12 (0.93) CA12CA6CA7CA9CA14
Spermidine SCHEMBL9144013 1.00 CA12 (0.93) CA12CA6CA7CA9CA14
SCHEMBL1460244 1.00 CA12 (0.93) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3974529-A1 NUCLEIC ACID, PHARMACEUTICAL COMPOSITION, CONJUGATE, PREPARATION METHOD, AND USE Suzhou Ribo Life Science Co., Ltd. (CN) 2022-03-30 EP disclosed
US-9114198-B2 Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2015-08-25 US disclosed
US-9034798-B2 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions CAPROTEC BIOANALYTICS GMBH (DE) 2015-05-19 US disclosed
US-8569481-B2 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions PHARMACEUTICALS, INC. (US) 2013-10-29 US disclosed
CN-102906159-A Amine polymers as bile acid sequestrants RELYPSA INC 2013-01-30 CN disclosed
US-8003123-B2 Biologically absorbable coatings for implantable devices and methods for fabricating the same ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2011-08-23 US disclosed
US-20110117161-A9 BIOLOGICALLY ABSORBABLE COATINGS FOR IMPLANTABLE DEVICES AND METHODS FOR FABRICATING THE SAME HOSSAINY SYED F A 2011-05-19 US disclosed
US-20110118136-A1 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions KOESTER HUBERT 2011-05-19 US disclosed
US-20100248264-A1 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions HK PHARMACEUTICALS, INC. 2010-09-30 US disclosed
US-20080206307-A1 BIOLOGICALLY ABSORBABLE COATINGS FOR IMPLANTABLE DEVICES AND METHODS FOR FABRICATING THE SAME HOSSAINY SYED F A 2008-08-28 US disclosed
US-7378106-B2 Biologically absorbable coatings for implantable devices and methods for fabricating the same ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2008-05-27 US disclosed
US-20070098758-A1 Biologically absorbable coatings for implantable devices and methods for fabricating the same ADVANCED CARDIOVASCULAR SYSTEMS 2007-05-03 US disclosed
US-7169404-B2 Biologically absorbable coatings for implantable devices and methods for fabricating the same ADVANCED CARDIOVASULAR SYSTEMS, INC. (US) 2007-01-30 US disclosed
US-20050143472-A1 Novel treatment for pathologies associated with oxidative damage REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2005-06-30 US disclosed
WO-2003068167-A2 NOVEL TREATMENT FOR PATHOLOGIES ASSOCIATED WITH OXIDATIVE DAMAGE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117161-A9 BIOLOGICALLY ABSORBABLE COATINGS FOR IMPLANTABLE DEVICES AND METHODS FOR FABRICATING THE SAME BMP2, BMP6, GUSB CA12 70/4885CA6 57/4885CA7 131/4885
US-20110118136-A1 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions PTMS, QPCTL, SRMS CA12 2071/4885CA6 2273/4885CA7 2423/4885
US-20080206307-A1 BIOLOGICALLY ABSORBABLE COATINGS FOR IMPLANTABLE DEVICES AND METHODS FOR FABRICATING THE SAME BMP2, BMP6, GUSB CA12 70/4885CA6 57/4885CA7 131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.