⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517085 | 0.72 | — | — | |
| SCHEMBL6514178 | 0.71 | DRD2 (0.36) | — | |
| SCHEMBL6910270 | 0.71 | CYP3A4 (0.30) | — | |
| SCHEMBL6905400 | 0.71 | — | — | |
| SCHEMBL5391535 | 0.70 | LMNA (0.30) | — | |
| SCHEMBL6369839 | 0.70 | HTR2A (0.42) | — | |
| Hydrochloric Acid SCHEMBL6514426 | 0.70 | — | — | |
| SCHEMBL6516981 | 0.69 | EP300 (0.34) | — | |
| SCHEMBL16488061 | 0.68 | — | — | |
| SCHEMBL6511985 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872863-B2 | Methylene bridged metallocenes as olefin-polymerization catalyst components | BASELL POLYOLEFINE GMBH (DE) | 2005-03-29 | — | — | US | disclosed |
| US-20040147695-A1 | Methylene bridged metallocenes as olefin-polymerization catalyst components | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-07-29 | — | — | US | disclosed |
| EP-1131328-B1 | METHYLENE BRIDGED METALLOCENES AS OLEFIN-POLYMERIZATION-CATALYST COMPONENTS | BASELL POLYOLEFINE GMBH (DE) | 2003-05-07 | — | — | EP | disclosed |