SCHEMBL6516981

SCHEMBL6516981

C=[Zr](Cl)(Cl)(C1=Cc2ccccc2C1Cc1ccccc1)C1=Cc2ccccc2C1Cc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.34
HTR2A P28223 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30605591 0.73 CALM1 (0.38) EP300HTR2A
SCHEMBL299429 0.73 CALM1 (0.38) EP300HTR2A
SCHEMBL16280617 0.72 CALM1 (0.37) EP300HTR2A
SCHEMBL6517085 0.72
SCHEMBL6514178 0.71 DRD2 (0.36)
SCHEMBL7194827 0.70 HTR2A (0.36) EP300HTR2A
SCHEMBL6925742 0.70 CES2 (0.36) EP300HTR2A
Hydrochloric Acid SCHEMBL6516976 0.70 HTR2A (0.33) EP300HTR2A
SCHEMBL6514432 0.69
SCHEMBL6511985 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6872863-B2 Methylene bridged metallocenes as olefin-polymerization catalyst components BASELL POLYOLEFINE GMBH (DE) 2005-03-29 US disclosed
US-20040147695-A1 Methylene bridged metallocenes as olefin-polymerization catalyst components BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-07-29 US disclosed
EP-1131328-B1 METHYLENE BRIDGED METALLOCENES AS OLEFIN-POLYMERIZATION-CATALYST COMPONENTS BASELL POLYOLEFINE GMBH (DE) 2003-05-07 EP disclosed