SCHEMBL6514461

SCHEMBL6514461

Cc1ccc(C(=O)CC(=C(CC(=O)O)C(=O)O)c2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.65
RAB9A P51151 6/20 0.65
NPC1 O15118 5/20 0.65
MEN1 O00255 4/20 0.65
RECQL P46063 1/20 0.48
HSD11B1 P28845 1/20 0.48
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47
CES1 P23141 2/20 0.47
CES2 O00748 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
MAPT P10636 3/20 0.47
CYP3A4 P08684 2/20 0.47
KDM4E B2RXH2 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
MAPK1 P28482 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ERCC5 P28715 2/20 0.46
FEN1 P39748 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6519565 1.00 KMT2A (0.65) KMT2ARAB9ANPC1MEN1RECQL
SCHEMBL6515905 0.95 NPC1 (0.56) KMT2ARAB9ANPC1MEN1RECQL
SCHEMBL6522224 0.91 MEN1 (0.57) KMT2ARAB9ANPC1MEN1LMNA
SCHEMBL6519120 0.85 SMN1; SMN2 (0.49) KMT2ARAB9ANPC1MEN1LMNA
SCHEMBL6518823 0.83 NPC1 (0.43) KMT2ARAB9ANPC1MEN1HSD11B1
SCHEMBL6520797 0.82 KMT2A (0.49) KMT2ARAB9ANPC1MEN1LMNA
SCHEMBL6518200 0.81 L3MBTL1 (0.49) KMT2ARAB9ANPC1MEN1LMNA
SCHEMBL6518786 0.81 NPC1 (0.58) KMT2ARAB9ANPC1MEN1HSD11B1
SCHEMBL6515517 0.81 SMN1; SMN2 (0.46) KMT2ARAB9ANPC1MEN1LMNA
SCHEMBL6523117 0.80 ELANE (0.44) KMT2ARAB9ANPC1MEN1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6958366-B2 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-25 US disclosed
US-20030118544-A1 Antifouling coating composition and novel resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2003-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030118544-A1 Antifouling coating composition and novel resin COL1A1, GLRA1, COL2A1 KMT2A 1067/4885RAB9A 2333/4885NPC1 3563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.