Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.63 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510594 | 0.92 | CNR1 (0.74) | CNR1 | |
| SCHEMBL4818837 | 0.82 | CNR1 (0.63) | CNR1CNR2 | |
| SCHEMBL6506416 | 0.78 | CNR1 (1.00) | CNR1 | |
| SCHEMBL6507095 | 0.77 | CNR1 (0.53) | CNR1LMNANPSR1 | |
| SCHEMBL4821388 | 0.74 | CNR1 (0.74) | CNR1 | |
| SCHEMBL4818931 | 0.73 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL4800431 | 0.70 | PTGS2 (0.54) | LMNANPSR1 | |
| SCHEMBL13496936 | 0.69 | CNR2 (0.68) | CNR1CNR2 | |
| SCHEMBL922639 | 0.69 | CNR2 (0.60) | CNR1CNR2 | |
| SCHEMBL6507282 | 0.68 | CNR1 (0.57) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | claimed |
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |