Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.53 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | PKLR | P30613 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510594 | 0.85 | CNR1 (0.74) | CNR1 | |
| SCHEMBL6514552 | 0.77 | CNR1 (0.63) | CNR1NPSR1LMNA | |
| SCHEMBL5381254 | 0.72 | ALDH1A1 (0.49) | CNR1ALDH1A1TDP1SMN1; SMN2PDE4B | |
| SCHEMBL22989951 | 0.71 | MAPT (0.48) | NPBWR1ALDH1A1HPGDTDP1PKM | |
| SCHEMBL1691901 | 0.70 | HTT (0.71) | NPBWR1ALDH1A1HPGDTDP1PKM | |
| SCHEMBL6506416 | 0.70 | CNR1 (1.00) | CNR1 | |
| SCHEMBL6511635 | 0.70 | BRD4 (0.44) | CNR1NPBWR1ALDH1A1HPGDTDP1 | |
| SCHEMBL25341629 | 0.68 | NPBWR1 (0.60) | NPBWR1ALDH1A1HPGDTDP1PKM | |
| SCHEMBL31174056 | 0.68 | HTT (0.59) | NPBWR1ALDH1A1HPGDTDP1PKM | |
| SCHEMBL4821388 | 0.68 | CNR1 (0.74) | CNR1ALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |