Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506347 | 0.82 | IKBKB (0.61) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL6509621 | 0.81 | SMN1; SMN2 (0.65) | PARP10RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL6507728 | 0.78 | IKBKB (0.50) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL24488964 | 0.78 | ALDH1A1 (0.61) | PARP10RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL6509110 | 0.78 | IKBKB (0.63) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6511724 | 0.77 | MAPT (0.51) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6530279 | 0.77 | IKBKB (0.48) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6505096 | 0.76 | IKBKB (0.47) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6512284 | 0.76 | CHEK1 (0.47) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6510633 | 0.76 | MEN1 (0.48) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105777-A1 | SUBSTITUTED THIOPHENE AMIDE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-11-10 | — | — | WO | disclosed |