Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12042732 | 0.83 | NOD2 (0.52) | NOD2NOD1NR1H2CACNA1BKDM4E | |
| SCHEMBL3030334 | 0.82 | NOD2 (0.46) | NOD2NOD1NR1H2KDM4ESMN1; SMN2 | |
| SCHEMBL1313682 | 0.81 | NOD2 (0.45) | NOD2NOD1NR1H2NR1H3SMN1; SMN2 | |
| SCHEMBL21685569 | 0.81 | NOD2 (0.45) | NOD2NOD1NR1H2KDM4EMEN1 | |
| SCHEMBL3023843 | 0.81 | NOD2 (0.45) | NOD2NOD1NR1H2NR1H3CACNA1B | |
| SCHEMBL6512126 | 0.80 | NOD2 (0.44) | NOD2NOD1NR1H2KDM4ESMN1; SMN2 | |
| SCHEMBL3036607 | 0.80 | MMP13 (0.47) | NOD2NOD1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24894603 | 0.79 | NOD2 (0.62) | NOD2NOD1NR1H2NR1H3KDM4E | |
| SCHEMBL29827958 | 0.79 | NOD2 (0.62) | NOD2NOD1NR1H2NR1H3KDM4E | |
| SCHEMBL12042731 | 0.79 | CYP4F2 (0.43) | NOD2NOD1NR1H2NR1H3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050026987-A1 | CBI analogues of the duocarmycins and CC-1065 | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026987-A1 | CBI analogues of the duocarmycins and CC-1065 | CCNI, SP1, DCK | NOD2 2070/4885NOD1 698/4885MDM2 1076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.