Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510816 | 0.91 | MEP1B (0.42) | MEP1BCYP2D6NR1H3PLA2G4BKCNH2 | |
| SCHEMBL6509306 | 0.88 | NR1H3 (0.40) | MEP1BNR1H3 | |
| SCHEMBL6518975 | 0.88 | FFAR1 (0.43) | MEP1BNR1H3HCRTR2 | |
| SCHEMBL6509514 | 0.87 | NR1H3 (0.40) | MEP1BNR1H3 | |
| SCHEMBL6507818 | 0.86 | KDM4E (0.38) | MEP1B | |
| SCHEMBL6511147 | 0.86 | TSHR (0.47) | — | |
| SCHEMBL6511871 | 0.85 | PPARA (0.39) | — | |
| SCHEMBL6516568 | 0.85 | PPARA (0.41) | — | |
| SCHEMBL6533434 | 0.84 | BCL2L1 (0.37) | MEP1BHCRTR2 | |
| SCHEMBL6531896 | 0.84 | FFAR4 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |