Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511871 | 0.97 | PPARA (0.39) | KDM4EPPARGPPARAS1PR1 | |
| SCHEMBL6516568 | 0.96 | PPARA (0.41) | PPARGPPARAS1PR1 | |
| SCHEMBL6515374 | 0.89 | ALDH1A1 (0.41) | S1PR1 | |
| SCHEMBL6508931 | 0.87 | CSF3R (0.39) | KDM4EHTTMEN1KMT2AMEP1B | |
| SCHEMBL6527447 | 0.86 | S1PR1 (0.43) | S1PR1 | |
| SCHEMBL6515031 | 0.86 | MEP1B (0.43) | MEP1B | |
| SCHEMBL6533434 | 0.85 | BCL2L1 (0.37) | KDM4EHTTMEN1MAPTKMT2A | |
| SCHEMBL6510860 | 0.83 | RAB9A (0.41) | PPARGPPARAHTTBCHE | |
| SCHEMBL6511147 | 0.82 | TSHR (0.47) | PPARGPPARA | |
| SCHEMBL6511749 | 0.82 | HTT (0.38) | KDM4EHTTMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |