Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 20/20 | 0.42 |
| ▸ | CTSS | P25774 | 20/20 | 0.42 |
| ▸ | CTSK | P43235 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14347626 | 0.86 | NAAA (0.40) | CTSLCTSS | |
| Hydrochloric Acid SCHEMBL5627174 | 0.85 | NAAA (0.39) | CTSLCTSS | |
| Hydrochloric Acid SCHEMBL5627163 | 0.85 | NAAA (0.39) | CTSLCTSS | |
| SCHEMBL7037265 | 0.82 | METAP2 (0.34) | CTSLCTSSCTSK | |
| SCHEMBL7039308 | 0.81 | METAP2 (0.33) | CTSLCTSSCTSK | |
| SCHEMBL7034077 | 0.80 | AAK1 (0.37) | — | |
| SCHEMBL7036267 | 0.78 | METAP2 (0.35) | CTSS | |
| SCHEMBL7037428 | 0.78 | AAK1 (0.35) | CTSK | |
| SCHEMBL7033232 | 0.77 | METAP2 (0.34) | CTSSCTSK | |
| SCHEMBL6515007 | 0.76 | CTSS (0.58) | CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082876-A1 | C-5 SUBSTITUTED FURANONE DIPEPTIDE CATHEPSIN S INHIBITORS | MEDIVIR UK LTD (GB) | 2005-09-09 | — | — | WO | disclosed |