SCHEMBL6515508

SCHEMBL6515508

CO[Si](CCCC#N)(C(C)C)C(C)C

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL712759 0.81
SCHEMBL705550 0.81
SCHEMBL4451456 0.81 TSHR (0.36) TSHR
SCHEMBL703350 0.75
SCHEMBL1584800 0.75 TSHR (0.42) TSHR
SCHEMBL126260 0.75 TSHR (0.42) TSHR
SCHEMBL332561 0.73
SCHEMBL235280 0.73 TSHR (0.40) TSHR
SCHEMBL387611 0.73 TSHR (0.40) TSHR
SCHEMBL6515585 0.71 NFKB1 (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150136700-A1 CHROMATOGRAPHIC MATERIALS WATERS TECHNOLOGIES CORPORATION (US) 2015-05-21 US disclosed
US-20050032084-A1 Method of attaching a biopolymer to a solid support DUKE UNIVERSITY (US) 2005-02-10 US disclosed
US-20020076832-A1 Method of attaching a biopolymer to a solid support DUKE UNIVERSITY 2002-06-20 US disclosed