Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 5/20 | 0.52 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP3 | P08254 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133806 | 0.83 | SOS1 (0.64) | SOS1HTTLMNASMN1; SMN2CA1 | |
| SCHEMBL17559302 | 0.82 | HTT (0.81) | SOS1HTTLMNASMN1; SMN2CA1 | |
| SCHEMBL11415437 | 0.82 | HTT (0.81) | SOS1HTTLMNASMN1; SMN2CA1 | |
| SCHEMBL6123058 | 0.82 | HTT (0.81) | SOS1HTTLMNASMN1; SMN2CA1 | |
| SCHEMBL146566 | 0.82 | HTT (0.81) | SOS1HTTLMNASMN1; SMN2CA1 | |
| SCHEMBL1462245 | 0.81 | SOS1 (0.62) | SOS1HTTLMNASMN1; SMN2CA1 | |
| Hydrochloric Acid SCHEMBL28805909 | 0.81 | SOS1 (0.62) | SOS1HTTLMNASMN1; SMN2CA1 | |
| SCHEMBL9323430 | 0.80 | HTT (0.78) | SOS1HTTLMNASMN1; SMN2CA1 | |
| Diphenylether SCHEMBL387430 | 0.79 | LTA4H (0.67) | SOS1HTTLMNASMN1; SMN2CA1 | |
| Diphenylether SCHEMBL8662108 | 0.79 | LTA4H (0.67) | SOS1HTTLMNASMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050137234-A1 | Histone deacetylase inhibitors | SYRRX, INC. | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137234-A1 | Histone deacetylase inhibitors | HDAC1, HDAC5, HDAC11 | SOS1 3608/4885HTT 3356/4885LMNA 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.