Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Diphenylether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.58 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | BAX | Q07812 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylether SCHEMBL8662108 | 1.00 | LTA4H (0.67) | LTA4HTSHRCA1CA2CA9 | |
| Diphenylether SCHEMBL1275631 | 0.97 | LTA4H (0.63) | LTA4HTSHRCA1CA2CA9 | |
| Diphenylether SCHEMBL29236471 | 0.97 | LTA4H (0.63) | LTA4HTSHRCA1CA2CA9 | |
| Diphenylether SCHEMBL1275630 | 0.97 | LTA4H (0.63) | LTA4HTSHRCA1CA2CA9 | |
| Diphenylether SCHEMBL8122150 | 0.97 | LTA4H (0.63) | LTA4HTSHRCA1CA2CA9 | |
| Diphenylether SCHEMBL9010428 | 0.95 | LTA4H (0.60) | LTA4HTSHRCA1CA2CA9 | |
| Diphenylether SCHEMBL28220689 | 0.92 | LTA4H (0.63) | LTA4HTSHRCA1CA2CA9 | |
| Diphenylether SCHEMBL17627919 | 0.90 | LTA4H (0.60) | LTA4HTSHRCA1CA2CA9 | |
| Diphenylether SCHEMBL11375805 | 0.90 | LTA4H (0.60) | LTA4HTSHRCA1CA2CA9 | |
| Diphenylether SCHEMBL6836277 | 0.89 | HTT (0.53) | LTA4HTSHRCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4108689-B1 | PROCESSING METHOD FOR CREAMING NATURAL LATEX | TIAN XIAOHUI (CN) | 2026-04-29 | — | — | EP | claimed |
| US-12565576-B2 | Deproteinized natural rubber latex and preparation method | Hunan Vontex New Material Technology Co., Ltd (CN) | 2026-03-03 | — | — | US | claimed |
| EP-4674877-A1 | SOLUTION TYPE BINDER, PREPARATION METHOD THEREFOR, AND USE THEREOF | Wanhua Chemical (Yantai) Battery Material Science Co., Ltd (CN) | 2026-01-07 | — | — | EP | claimed |
| CN-119823681-A | Water-based negative electrode binder of lithium ion battery, preparation method and application thereof | 万华化学集团电池科技有限公司 | 2025-04-15 | — | — | CN | claimed |
| WO-2025055178-A1 | SOLUTION TYPE BINDER, PREPARATION METHOD THEREFOR, AND USE THEREOF | 万华化学(烟台)电池材料科技有限公司 | 2025-03-20 | — | — | WO | claimed |
| US-20240239999-A1 | DEPROTEINIZED NATURAL RUBBER LATEX AND PREPARATION METHOD | Hunan Vontex New Material Technology Co., Ltd. (CN) | 2024-07-18 | — | — | US | claimed |
| WO-2024099751-A1 | AQUEOUS RADIATION CURABLE COMPOSITION | ALLNEX BELGIUM, S.A. (BE) | 2024-05-16 | — | — | WO | claimed |
| US-11952437-B2 | Processing method of natural rubber latex using creaming | Tian, Xiaohui (CN) | 2024-04-09 | — | — | US | claimed |
| CN-117447625-A | Milk precipitation processing method of natural latex | 田晓慧 | 2024-01-26 | — | — | CN | claimed |
| CN-117050237-A | Solution type binder and preparation method and application thereof | 万华化学(烟台)电池材料科技有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-101512012-A | Method for quantifying cholesterol in small, dense low-density lipoprotein | KYOWA MEDEX CO LTD (JP) | 2009-08-19 | — | — | CN | claimed |
| CN-101326289-A | Method for determination of cholesterol level in remnant-like lipoprotein, reagent and kit | KYOWA MEDEX CO LTD (JP) | 2008-12-17 | — | — | CN | claimed |
| US-20080245989-A1 | EMULSION FOR VIBRATION DAMPING MATERIALS | NIPPON SHOKUBAI CO., LTD. (JP) | 2008-10-09 | — | — | US | claimed |
| EP-1953240-A1 | METHOD FOR MEASURING TRIGLYCERIDE IN LOW-DENSITY LIPOPROTEIN AND KIT FOR MEASUREMENT | Kyowa Medex Co., Ltd. (JP) | 2008-08-06 | — | — | EP | claimed |
| US-20060014229-A1 | Method and reagent for measuring cholesterol in high density lipoproteins | KYOWA MEDEX CO., LTD (JP) | 2006-01-19 | — | — | US | claimed |
| CN-1649951-A | Agent for suppressing transfer of odor and taste originating from a diacetal, a diacetal composition comprising the agent for suppressing transfer of odor and taste, a polyolefin nucleating agent comp | NEW JAPAN CHEM CO LTD (JP) | 2005-08-03 | — | — | CN | claimed |
| EP-1555326-A1 | METHOD AND REAGENT FOR MEASURING CHOLESTEROL IN HIGH DENSITY LIPOPROTEINS | Kyowa Medex Co., Ltd. (JP) | 2005-07-20 | — | — | EP | claimed |
| CN-1500120-A | Diacetal composition, polyolefin nucleating agent containing the diacetal composition, polyolefin resin composition containing the diacetal composition, process for producing the resin composition, and molded article | 新日本理化株式会社 | 2004-05-26 | — | — | CN | claimed |
| EP-0228575-B1 | METHODS FOR MAKING POLYDIORGANOSILOXANE MICROEMULSIONS | DOW CORNING CORPORATION (US) | 1993-02-03 | — | — | EP | claimed |
| US-4088596-A | INORGANIC PEROXIDE | KAO SOAP CO., LTD. (JA) | 1978-05-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12565576-B2 | Deproteinized natural rubber latex and preparation method | AGL, MGAM, PGLS | MAOA 2349/4885LTA4H 394/4885TSHR 2651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.