Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4500247 | 0.83 | SMN1; SMN2 (0.38) | LMNAHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL25211116 | 0.83 | SMN1; SMN2 (0.38) | LMNAALDH1A1HSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL13393366 | 0.83 | NISCH (0.40) | LMNASMN1; SMN2PDE3BPDE3AHDAC8 | |
| SCHEMBL9668468 | 0.83 | ESR2 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL15088368 | 0.80 | ADRA2A (0.40) | SMN1; SMN2HDAC8ADRA2AADRA1ACYP1A2 | |
| SCHEMBL1842317 | 0.78 | SMN1; SMN2 (0.48) | ALDH1A1HPGDHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL15706601 | 0.76 | NISCH (0.36) | SMN1; SMN2PDE3BPDE3A | |
| Bromide SCHEMBL5635020 | 0.75 | SMN1; SMN2 (0.46) | ALDH1A1HPGDHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL4044503 | 0.75 | SMN1; SMN2 (0.35) | ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL10339321 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087382-A1 | Inhibitors of Hepatitis C NS3 Protease | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-08 | — | — | US | disclosed |
| US-20050142413-A1 | Separator for fuel cell, method for producing the same, and fuel cell using the same | SANSHO KAKOU CO., LTD. (JP) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087382-A1 | Inhibitors of Hepatitis C NS3 Protease | RNASE1, GTF3C3, CTRL | LMNA 2842/4885TP53 705/4885ALDH1A1 939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.